Abstract
Heparin is a polydisperse, highly sulfated, linear polysaccharide of repeating uronic acid and glucosamine residues. Heparin's primary application is an an anticoagulant, however, it is more appropriate to consider heparin in a polyelectrolytic drug having a multiplicity of biological activities. Low molecular weight heparins and heparinoids have been undergoing clinical trials as anticoagulant/antithrombotic agents for use in a wide variety of disease states ranging from deep vein thrombosis to non-hemmorrhagic stroke. These agents include both natural products chemically or enzymatically derived from heparin as well as fully synthetic acidic oligosaccharides and polysaccharides.
| Original language | English |
|---|---|
| Pages (from-to) | 488-491 |
| Number of pages | 4 |
| Journal | Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering |
| Volume | 62 |
| State | Published - 1990 |
| Externally published | Yes |
| Event | Proceedings of the ACS Division of Polymeric Materials: Science and Engineering - Boston, MA, USA Duration: 1 Apr 1990 → 1 Apr 1990 |