Modelling the occurrence and pathology of Alzheimer's disease

J. A. Hardy; A. M. Goate; M. J. Owen; M. J. Mullan; M. N. Rossor; R. C.A. Pearson

doi:10.1016/0197-4580(89)90084-5

Modelling the occurrence and pathology of Alzheimer's disease

J. A. Hardy, A. M. Goate, M. J. Owen, M. J. Mullan, M. N. Rossor, R. C.A. Pearson

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.

Original language	English
Pages (from-to)	429-431
Number of pages	3
Journal	Neurobiology of Aging
Volume	10
Issue number	5
DOIs	https://doi.org/10.1016/0197-4580(89)90084-5
State	Published - 1989
Externally published	Yes

Access to Document

10.1016/0197-4580(89)90084-5

Cite this

@article{24fe7e12f0364b3391974c9b84c93740,

title = "Modelling the occurrence and pathology of Alzheimer's disease",

abstract = "Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.",

author = "Hardy, {J. A.} and Goate, {A. M.} and Owen, {M. J.} and Mullan, {M. J.} and Rossor, {M. N.} and Pearson, {R. C.A.}",

year = "1989",

doi = "10.1016/0197-4580(89)90084-5",

language = "English",

volume = "10",

pages = "429--431",

journal = "Neurobiology of Aging",

issn = "0197-4580",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Modelling the occurrence and pathology of Alzheimer's disease

AU - Hardy, J. A.

AU - Goate, A. M.

AU - Owen, M. J.

AU - Mullan, M. J.

AU - Rossor, M. N.

AU - Pearson, R. C.A.

PY - 1989

Y1 - 1989

N2 - Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.

AB - Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.

UR - http://www.scopus.com/inward/record.url?scp=0024367314&partnerID=8YFLogxK

U2 - 10.1016/0197-4580(89)90084-5

DO - 10.1016/0197-4580(89)90084-5

M3 - Article

C2 - 2812201

AN - SCOPUS:0024367314

SN - 0197-4580

VL - 10

SP - 429

EP - 431

JO - Neurobiology of Aging

JF - Neurobiology of Aging

IS - 5

ER -

Modelling the occurrence and pathology of Alzheimer's disease

Abstract

Access to Document

Fingerprint

Cite this