Modelling the occurrence and pathology of Alzheimer's disease

J. A. Hardy, A. M. Goate, M. J. Owen, M. J. Mullan, M. N. Rossor, R. C.A. Pearson

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.

Original languageEnglish
Pages (from-to)429-431
Number of pages3
JournalNeurobiology of Aging
Issue number5
StatePublished - 1989
Externally publishedYes


Dive into the research topics of 'Modelling the occurrence and pathology of Alzheimer's disease'. Together they form a unique fingerprint.

Cite this