Modelling spatio-temporal interactions within the cell

Padmini Rangamani, Ravi Iyengar

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Biological phenomena at the cellular level can be represented by various types of mathematical formulations. Such representations allow us to carry out numerical simulations that provide mechanistic insights into complex behaviours of biological systems and also generate hypotheses that can be experimentally tested. Currently, we are particularly interested in spatio-temporal representations of dynamic cellular phenomena and how such models can be used to understand biological specificity in functional responses. This review describes the capability and limitations of the approaches used to study spatio-temporal dynamics of cell signalling components.

Original languageEnglish
Pages (from-to)157-167
Number of pages11
JournalJournal of Biosciences
Volume32
Issue number1
DOIs
StatePublished - Jan 2007

Keywords

  • Cell signalling
  • Modelling
  • Spatio-temporal interactions

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