@inbook{5e34e4011eb04a0081d569dfa9bb0d5a,
title = "Modeling leukemia stem cells with patient-derived induced pluripotent stem cells",
abstract = "Patient-derived induced pluripotent stem cells (iPSCs) have recently provided a new way to model acute myeloid leukemia (AML) and other myeloid malignancies. Here, we describe methods for the generation of patient-derived iPSCs from leukemia cells and for their subsequent directed in vitro differentiation into hematopoietic cells that recapitulate features of leukemia stem cells (LSCs) and leukemic blasts.",
keywords = "AML, Human induced pluripotent stem cells, Reprogramming, hPSC-hematopoiesis, iPSC disease modeling",
author = "Deslauriers, \{Andr{\'e} G.\} and Kotini, \{Andriana G.\} and Papapetrou, \{Eirini P.\}",
note = "Publisher Copyright: {\textcopyright} 2021, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2021",
doi = "10.1007/978-1-0716-0810-4\_26",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "411--422",
booktitle = "Methods in Molecular Biology",
}