Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation

Frederick R. Adler; Alexander R.A. Anderson; Abhinav Bhushan; Paul Bogdan; Jose Javier Bravo-Cordero; Amy Brock; Yun Chen; Edna Cukierman; Kathleen E. DelGiorno; Gerald V. Denis; Meghan C. Ferrall-Fairbanks; Zev Jordan Gartner; Ronald N. Germain; Deborah M. Gordon; Ginger Hunter; Mohit Kumar Jolly; Loukia Georgiou Karacosta; Karthikeyan Mythreye; Parag Katira; Rajan P. Kulkarni; Matthew L. Kutys; Arthur D. Lander; Ashley M. Laughney; Herbert Levine; Emil Lou; Pedro R. Lowenstein; Kristyn S. Masters; Dana Pe'er; Shelly R. Peyton; Manu O. Platt; Jeremy E. Purvis; Gerald Quon; Jennifer K. Richer; Nicole C. Riddle; Analiz Rodriguez; Joshua C. Snyder; Gregory Lee Szeto; Claire J. Tomlin; Itai Yanai; Ioannis K. Zervantonakis; Hannah Dueck

doi:10.1016/j.cels.2023.03.002

Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation

Frederick R. Adler
, Alexander R.A. Anderson
, Abhinav Bhushan
, Paul Bogdan
, Jose Javier Bravo-Cordero
, Amy Brock
, Yun Chen
, Edna Cukierman
, Kathleen E. DelGiorno
, Gerald V. Denis
, Meghan C. Ferrall-Fairbanks
, Zev Jordan Gartner
, Ronald N. Germain
, Deborah M. Gordon
, Ginger Hunter
, Mohit Kumar Jolly
, Loukia Georgiou Karacosta
, Karthikeyan Mythreye
, Parag Katira
, Rajan P. Kulkarni

Matthew L. Kutys, Arthur D. Lander, Ashley M. Laughney, Herbert Levine, Emil Lou, Pedro R. Lowenstein, Kristyn S. Masters, Dana Pe'er, Shelly R. Peyton, Manu O. Platt, Jeremy E. Purvis, Gerald Quon, Jennifer K. Richer, Nicole C. Riddle, Analiz Rodriguez, Joshua C. Snyder, Gregory Lee Szeto, Claire J. Tomlin, Itai Yanai, Ioannis K. Zervantonakis, Hannah Dueck

Research output: Contribution to journal › Comment/debate

9 Scopus citations

Abstract

Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.

Original language	English
Pages (from-to)	252-257
Number of pages	6
Journal	Cell Systems
Volume	14
Issue number	4
DOIs	https://doi.org/10.1016/j.cels.2023.03.002
State	Published - 19 Apr 2023

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Adler, F. R., Anderson, A. R. A., Bhushan, A., Bogdan, P., Bravo-Cordero, J. J., Brock, A., Chen, Y., Cukierman, E., DelGiorno, K. E., Denis, G. V., Ferrall-Fairbanks, M. C., Gartner, Z. J., Germain, R. N., Gordon, D. M., Hunter, G., Jolly, M. K., Karacosta, L. G., Mythreye, K., Katira, P., ... Dueck, H. (2023). Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell Systems, 14(4), 252-257. https://doi.org/10.1016/j.cels.2023.03.002

@article{144befbbeed9445f897060ae91fee315,

title = "Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation",

abstract = "Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.",

author = "Adler, \{Frederick R.\} and Anderson, \{Alexander R.A.\} and Abhinav Bhushan and Paul Bogdan and Bravo-Cordero, \{Jose Javier\} and Amy Brock and Yun Chen and Edna Cukierman and DelGiorno, \{Kathleen E.\} and Denis, \{Gerald V.\} and Ferrall-Fairbanks, \{Meghan C.\} and Gartner, \{Zev Jordan\} and Germain, \{Ronald N.\} and Gordon, \{Deborah M.\} and Ginger Hunter and Jolly, \{Mohit Kumar\} and Karacosta, \{Loukia Georgiou\} and Karthikeyan Mythreye and Parag Katira and Kulkarni, \{Rajan P.\} and Kutys, \{Matthew L.\} and Lander, \{Arthur D.\} and Laughney, \{Ashley M.\} and Herbert Levine and Emil Lou and Lowenstein, \{Pedro R.\} and Masters, \{Kristyn S.\} and Dana Pe'er and Peyton, \{Shelly R.\} and Platt, \{Manu O.\} and Purvis, \{Jeremy E.\} and Gerald Quon and Richer, \{Jennifer K.\} and Riddle, \{Nicole C.\} and Analiz Rodriguez and Snyder, \{Joshua C.\} and \{Lee Szeto\}, Gregory and Tomlin, \{Claire J.\} and Itai Yanai and Zervantonakis, \{Ioannis K.\} and Hannah Dueck",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

month = apr,

day = "19",

doi = "10.1016/j.cels.2023.03.002",

language = "English",

volume = "14",

pages = "252--257",

journal = "Cell Systems",

issn = "2405-4712",

publisher = "Cell Press",

number = "4",

}

Adler, FR, Anderson, ARA, Bhushan, A, Bogdan, P, Bravo-Cordero, JJ, Brock, A, Chen, Y, Cukierman, E, DelGiorno, KE, Denis, GV, Ferrall-Fairbanks, MC, Gartner, ZJ, Germain, RN, Gordon, DM, Hunter, G, Jolly, MK, Karacosta, LG, Mythreye, K, Katira, P, Kulkarni, RP, Kutys, ML, Lander, AD, Laughney, AM, Levine, H, Lou, E, Lowenstein, PR, Masters, KS, Pe'er, D, Peyton, SR, Platt, MO, Purvis, JE, Quon, G, Richer, JK, Riddle, NC, Rodriguez, A, Snyder, JC, Lee Szeto, G, Tomlin, CJ, Yanai, I, Zervantonakis, IK & Dueck, H 2023, 'Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation', Cell Systems, vol. 14, no. 4, pp. 252-257. https://doi.org/10.1016/j.cels.2023.03.002

TY - JOUR

T1 - Modeling collective cell behavior in cancer

T2 - Perspectives from an interdisciplinary conversation

AU - Adler, Frederick R.

AU - Anderson, Alexander R.A.

AU - Bhushan, Abhinav

AU - Bogdan, Paul

AU - Bravo-Cordero, Jose Javier

AU - Brock, Amy

AU - Chen, Yun

AU - Cukierman, Edna

AU - DelGiorno, Kathleen E.

AU - Denis, Gerald V.

AU - Ferrall-Fairbanks, Meghan C.

AU - Gartner, Zev Jordan

AU - Germain, Ronald N.

AU - Gordon, Deborah M.

AU - Hunter, Ginger

AU - Jolly, Mohit Kumar

AU - Karacosta, Loukia Georgiou

AU - Mythreye, Karthikeyan

AU - Katira, Parag

AU - Kulkarni, Rajan P.

AU - Kutys, Matthew L.

AU - Lander, Arthur D.

AU - Laughney, Ashley M.

AU - Levine, Herbert

AU - Lou, Emil

AU - Lowenstein, Pedro R.

AU - Masters, Kristyn S.

AU - Pe'er, Dana

AU - Peyton, Shelly R.

AU - Platt, Manu O.

AU - Purvis, Jeremy E.

AU - Quon, Gerald

AU - Richer, Jennifer K.

AU - Riddle, Nicole C.

AU - Rodriguez, Analiz

AU - Snyder, Joshua C.

AU - Lee Szeto, Gregory

AU - Tomlin, Claire J.

AU - Yanai, Itai

AU - Zervantonakis, Ioannis K.

AU - Dueck, Hannah

PY - 2023/4/19

Y1 - 2023/4/19

N2 - Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.

AB - Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.

UR - https://www.scopus.com/pages/publications/85152230264

U2 - 10.1016/j.cels.2023.03.002

DO - 10.1016/j.cels.2023.03.002

M3 - Comment/debate

AN - SCOPUS:85152230264

SN - 2405-4712

VL - 14

SP - 252

EP - 257

JO - Cell Systems

JF - Cell Systems

IS - 4

ER -

Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation

Abstract

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