Mitochondrial related genome-wide Mendelian randomization identifies putatively causal genes for multiple cancer types

Keyphrases

• Breast Cancer Risk 100%
• Causal Genes 100%
• Mitochondrial Dysfunction 100%
• Mendelian Randomization 100%
• Mendelian Randomization Analysis 100%
• Multiple Cancer Types 100%
• Methylation Status 66%
• Expression Level 66%
• Prostate Cancer Risk 66%
• Mitochondrial Genes 66%
• Lung Cancer 33%
• DNA Methylation (DNAm) 33%
• Melanoma 33%
• Gene Expression 33%
• Causal Relationship 33%
• Risk Loci 33%
• Cancer Types 33%
• Protein Expression 33%
• Sensitivity Analysis 33%
• European Ancestry 33%
• Cancer Causes 33%
• Breast 33%
• Common Cancers 33%
• Causal Role 33%
• Genetic Variants 33%
• Lung Cancer Risk 33%
• Colocalization 33%
• Cancer Risk 33%
• Cancer Prevention 33%
• Protein-DNA Complex 33%
• Prostate 33%
• Risk Variant 33%
• Expression Quantitative Trait Loci (eQTL) 33%
• Regulatory Mechanism 33%
• Colocalization Analysis 33%
• Pharmacological Agents 33%
• Data-centric 33%
• Multiple Cancers 33%
• In Cis 33%
• Cancer Hallmarks 33%
• Causal Association 33%
• Causal Effect 33%
• Molecular Alterations 33%
• Randomized Methods 33%
• Causal Inference 33%
• Malm 33%
• Genetic Instruments 33%
• Protein Quantitative Trait Loci 33%
• MR Analysis 33%
• Bayesian Hypothesis Testing 33%
• Casual Association 33%
• VARS2 33%
• Molecular QTL 33%

Biochemistry, Genetics and Molecular Biology

• Mendelian Randomization 100%
• Mitochondrial Disorder 60%
• Methylation 40%
• Genetics 20%
• DNA Methylation 20%
• Candidate Gene 20%
• Gene Expression 20%
• Genetic Divergence 20%
• Protein Expression 20%
• Expression Quantitative Trait Loci 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Multiple Cancer 100%
• Breast Cancer 50%
• Prostate Cancer 33%
• Lung Cancer 33%
• Melanoma 16%