Mitigation of speckle noise in optical coherence tomograms

Saba Adabi, Anne Clayton, Silvia Conforto, Ali Hojjat, Adrian G. Podoleanu, Mohammadreza Nasiriavanaki

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations


Optical Coherence Tomography (OCT) is a promising high-resolution imaging technique that works based on low coherent interferometry. However, like other low coherent imaging modalities, OCT suffers from an artifact called, speckle. Speckle reduces the detectability of diagnostically relevant features in the tissue. Retinal optical coherence tomograms are of a great importance in detecting and diagnosing eye diseases. Different hardware or software based techniques are devised in literatures to mitigate speckle noise. The ultimate aim of any software-based despeckling technique is to suppress the noise part of speckle while preserves the information carrying portion of that. In this chapter, we reviewed the most prominent speckle reduction methods for OCT images to date and then present a novel and intelligent speckle reduction algorithm to reduce speckle in OCT images of retina, based on an ensemble framework of Multi-Layer Perceptron (MLP) neural networks.

Original languageEnglish
Title of host publicationSpringer Series in Optical Sciences
PublisherSpringer Verlag
Number of pages21
StatePublished - 2018
Externally publishedYes

Publication series

NameSpringer Series in Optical Sciences
ISSN (Print)0342-4111
ISSN (Electronic)1556-1534


  • Artificial neural network (ANN)
  • Multi-Layer perceptron (MLP)
  • Optical coherence tomography
  • Speckle noise reduction


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