Radiesse™ or calcium hydroxylapatite has been used for years in patients with HIV associated lipoatrophy  as well as for facial wrinkles and nasolabial folds [2, 3], but can be painful to inject especially in the latter area. This discomfort can be severe enough that after an injection with Radiesse™, a patient, despite excellent results, may refuse additional treatments. We hereby describe several methods of minimizing discomfort during Radiesse™ injections of nasolabial folds and other facial areas.
|Journal||Dermatology Online Journal|
|State||Published - Jul 2007|