TY - JOUR
T1 - Military Blast Injury and Chronic Neurodegeneration
T2 - Research Presentations from the 2015 International State-of-The-Science Meeting
AU - Agoston, Denes
AU - Arun, Peethambaran
AU - Bellgowan, Patrick
AU - Broglio, Steven
AU - Cantu, Robert
AU - Cook, David
AU - Da Silva, Uade Olaghere
AU - Dickstein, Dara
AU - Elder, Gregory
AU - Fudge, Elizabeth
AU - Gandy, Sam
AU - Gill, Jessica
AU - Glenn, John F.
AU - Gupta, Raj K.
AU - Hinds, Sidney
AU - Hoffman, Stuart
AU - Lattimore, Theresa
AU - Lin, Alexander
AU - Lu, Kun Ping
AU - Maroon, Joseph
AU - Okonkwo, David
AU - Perl, Daniel
AU - Robinson, Meghan
AU - Rosen, Charles
AU - Smith, Douglas
N1 - Publisher Copyright:
© Copyright 2017, Mary Ann Liebert, Inc. 2017.
PY - 2017/9
Y1 - 2017/9
N2 - Blast-related traumatic brain injury (TBI) is a signature injury of recent military conflicts, leading to increased Department of Defense (DoD) interest in its potential long-Term effects, such as chronic traumatic encephalopathy (CTE). The DoD Blast Injury Research Program Coordinating Office convened the 2015 International State-of-The-Science Meeting to discuss the existing evidence regarding a causal relationship between TBI and CTE. Over the course of the meeting, experts across government, academia, and the sports community presented cutting edge research on the unique pathological characteristics of blast-related TBI, blast-related neurodegenerative mechanisms, risk factors for CTE, potential biomarkers for CTE, and treatment strategies for chronic neurodegeneration. The current paper summarizes these presentations. Although many advances have been made to address these topics, more research is needed to establish the existence of links between the long-Term effects of single or multiple blast-related TBI and CTE.
AB - Blast-related traumatic brain injury (TBI) is a signature injury of recent military conflicts, leading to increased Department of Defense (DoD) interest in its potential long-Term effects, such as chronic traumatic encephalopathy (CTE). The DoD Blast Injury Research Program Coordinating Office convened the 2015 International State-of-The-Science Meeting to discuss the existing evidence regarding a causal relationship between TBI and CTE. Over the course of the meeting, experts across government, academia, and the sports community presented cutting edge research on the unique pathological characteristics of blast-related TBI, blast-related neurodegenerative mechanisms, risk factors for CTE, potential biomarkers for CTE, and treatment strategies for chronic neurodegeneration. The current paper summarizes these presentations. Although many advances have been made to address these topics, more research is needed to establish the existence of links between the long-Term effects of single or multiple blast-related TBI and CTE.
KW - blast injury
KW - chronic traumatic encephalopathy
KW - neurodegeneration
KW - repetitive head trauma
KW - traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=85029799598&partnerID=8YFLogxK
U2 - 10.1089/neu.2017.5220
DO - 10.1089/neu.2017.5220
M3 - Article
C2 - 28937955
AN - SCOPUS:85029799598
SN - 0897-7151
VL - 34
SP - S6-S17
JO - Journal of Neurotrauma
JF - Journal of Neurotrauma
IS - S1
ER -