Mild traumatic brain injury and attention-deficit hyperactivity disorder in young student athletes

Joseph Biederman; Leah Feinberg; James Chan; Bamidele O. Adeyemo; K. Yvonne Woodworth; Walter Panis; Neal McGrath; Saurabha Bhatnagar; Thomas J. Spencer; Mai Uchida; Tara Kenworthy; Rebecca Grossman; Ross Zafonte; Stephen V. Faraone

doi:10.1097/NMD.0000000000000375

Mild traumatic brain injury and attention-deficit hyperactivity disorder in young student athletes

Joseph Biederman, Leah Feinberg, James Chan, Bamidele O. Adeyemo, K. Yvonne Woodworth, Walter Panis, Neal McGrath, Saurabha Bhatnagar, Thomas J. Spencer, Mai Uchida, Tara Kenworthy, Rebecca Grossman, Ross Zafonte, Stephen V. Faraone

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

A recent meta-analysis documented a significant statistical association between mild traumatic brain injury (mTBI) and attention deficit hyperactivity disorder (ADHD) (Adeyemo et al., 2014), but the direction of this effect was unclear. In this study, we hypothesized that ADHD would be an antecedent risk factor for mTBI. Participants were student athletes ages 12 to 25 who had sustained a mTBI and Controls of similar age and sex selected from studies of youth with and without ADHD. Subjects were assessed for symptoms of ADHD, concussion severity, and cognitive function. mTBI subjects had a significantly higher rate of ADHD than Controls, and in all cases the age of onset of ADHD was before mTBI onset. mTBI+ADHD subjects also had more severe concussion symptoms (fatigue and poor concentration) than mTBI-ADHD subjects. These results support ADHD as an antecedent risk factor for mTBI in student athletes and that its presence complicates the course of mTBI.

Original language	English
Pages (from-to)	813-819
Number of pages	7
Journal	Journal of Nervous and Mental Disease
Volume	203
Issue number	11
DOIs	https://doi.org/10.1097/NMD.0000000000000375
State	Published - 2015
Externally published	Yes

Keywords

Attention-deficit hyperactivity disorder
Mild
Student athlete
Traumatic brain injury

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10.1097/NMD.0000000000000375

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Biederman, J., Feinberg, L., Chan, J., Adeyemo, B. O., Woodworth, K. Y., Panis, W., McGrath, N., Bhatnagar, S., Spencer, T. J., Uchida, M., Kenworthy, T., Grossman, R., Zafonte, R., & Faraone, S. V. (2015). Mild traumatic brain injury and attention-deficit hyperactivity disorder in young student athletes. Journal of Nervous and Mental Disease, 203(11), 813-819. https://doi.org/10.1097/NMD.0000000000000375

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title = "Mild traumatic brain injury and attention-deficit hyperactivity disorder in young student athletes",

abstract = "A recent meta-analysis documented a significant statistical association between mild traumatic brain injury (mTBI) and attention deficit hyperactivity disorder (ADHD) (Adeyemo et al., 2014), but the direction of this effect was unclear. In this study, we hypothesized that ADHD would be an antecedent risk factor for mTBI. Participants were student athletes ages 12 to 25 who had sustained a mTBI and Controls of similar age and sex selected from studies of youth with and without ADHD. Subjects were assessed for symptoms of ADHD, concussion severity, and cognitive function. mTBI subjects had a significantly higher rate of ADHD than Controls, and in all cases the age of onset of ADHD was before mTBI onset. mTBI+ADHD subjects also had more severe concussion symptoms (fatigue and poor concentration) than mTBI-ADHD subjects. These results support ADHD as an antecedent risk factor for mTBI in student athletes and that its presence complicates the course of mTBI.",

keywords = "Attention-deficit hyperactivity disorder, Mild, Student athlete, Traumatic brain injury",

author = "Joseph Biederman and Leah Feinberg and James Chan and Adeyemo, {Bamidele O.} and Woodworth, {K. Yvonne} and Walter Panis and Neal McGrath and Saurabha Bhatnagar and Spencer, {Thomas J.} and Mai Uchida and Tara Kenworthy and Rebecca Grossman and Ross Zafonte and Faraone, {Stephen V.}",

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Biederman, J, Feinberg, L, Chan, J, Adeyemo, BO, Woodworth, KY, Panis, W, McGrath, N, Bhatnagar, S, Spencer, TJ, Uchida, M, Kenworthy, T, Grossman, R, Zafonte, R & Faraone, SV 2015, 'Mild traumatic brain injury and attention-deficit hyperactivity disorder in young student athletes', Journal of Nervous and Mental Disease, vol. 203, no. 11, pp. 813-819. https://doi.org/10.1097/NMD.0000000000000375

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AU - Panis, Walter

AU - McGrath, Neal

AU - Bhatnagar, Saurabha

AU - Spencer, Thomas J.

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AU - Kenworthy, Tara

AU - Grossman, Rebecca

AU - Zafonte, Ross

AU - Faraone, Stephen V.

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Mild traumatic brain injury and attention-deficit hyperactivity disorder in young student athletes

Abstract

Keywords

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