Mild cognitive impairment and dementia

Marilyn S. Albert; Deborah Blacker

doi:10.1146/annurev.clinpsy.1.102803.144039

Mild cognitive impairment and dementia

Marilyn S. Albert, Deborah Blacker

Research output: Contribution to journal › Review article › peer-review

46 Scopus citations

Abstract

Mild cognitive impairment (MCI) is a clinical syndrome thought to represent the transition between normal function and dementia. This review describes data that support the existence of such a transitional phase, outlines the heterogeneity of MCI and how that has influenced the evolving concept of MCI, and discusses the impact of heterogeneity on recent MCI clinical trials.

Original language	English
Pages (from-to)	379-388
Number of pages	10
Journal	Annual Review of Clinical Psychology
Volume	2
DOIs	https://doi.org/10.1146/annurev.clinpsy.1.102803.144039
State	Published - 2006
Externally published	Yes

Keywords

APOE
Alzheimer's disease
Biomarkers
Clinical trials
MCI

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10.1146/annurev.clinpsy.1.102803.144039

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title = "Mild cognitive impairment and dementia",

abstract = "Mild cognitive impairment (MCI) is a clinical syndrome thought to represent the transition between normal function and dementia. This review describes data that support the existence of such a transitional phase, outlines the heterogeneity of MCI and how that has influenced the evolving concept of MCI, and discusses the impact of heterogeneity on recent MCI clinical trials.",

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AU - Blacker, Deborah

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AB - Mild cognitive impairment (MCI) is a clinical syndrome thought to represent the transition between normal function and dementia. This review describes data that support the existence of such a transitional phase, outlines the heterogeneity of MCI and how that has influenced the evolving concept of MCI, and discusses the impact of heterogeneity on recent MCI clinical trials.

KW - APOE

KW - Alzheimer's disease

KW - Biomarkers

KW - Clinical trials

KW - MCI

UR - https://www.scopus.com/pages/publications/33744473043

U2 - 10.1146/annurev.clinpsy.1.102803.144039

DO - 10.1146/annurev.clinpsy.1.102803.144039

M3 - Review article

C2 - 17716075

AN - SCOPUS:33744473043

SN - 1548-5943

VL - 2

SP - 379

EP - 388

JO - Annual Review of Clinical Psychology

JF - Annual Review of Clinical Psychology

ER -

Mild cognitive impairment and dementia

Abstract

Keywords

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