TY - JOUR
T1 - Middle Meningeal Artery Embolization in Chronic Subdural Hematoma
T2 - Implications of Pathophysiology in Trial Design
AU - Moshayedi, Pouria
AU - Liebeskind, David S.
N1 - Publisher Copyright:
© Copyright © 2020 Moshayedi and Liebeskind.
PY - 2020/8/27
Y1 - 2020/8/27
N2 - Background: Chronic subdural hematoma (cSDH) is a debilitating condition with a high rate of recurrence after surgical evacuation. Summary: This review is focused on middle meningeal artery (MMA) embolization to treat cSDH. We discuss the underlying pathophysiology of chronic subdural hematoma and how cessation of arterial flow may resolve a venous hemorrhage. We also present the current evidence for MMA embolization and the roadmap for future trials. Conclusion: Frequent multimodal imaging and cSDH sampling would enable us to understand mechanisms of MMA embolization in cSDH treatment and therefore improve our ability to offer MMA embolization to the eligible population.
AB - Background: Chronic subdural hematoma (cSDH) is a debilitating condition with a high rate of recurrence after surgical evacuation. Summary: This review is focused on middle meningeal artery (MMA) embolization to treat cSDH. We discuss the underlying pathophysiology of chronic subdural hematoma and how cessation of arterial flow may resolve a venous hemorrhage. We also present the current evidence for MMA embolization and the roadmap for future trials. Conclusion: Frequent multimodal imaging and cSDH sampling would enable us to understand mechanisms of MMA embolization in cSDH treatment and therefore improve our ability to offer MMA embolization to the eligible population.
KW - chronic subdural hematoma
KW - embolization
KW - endovascular treatment
KW - interventional neuroradiology
KW - middle meningeal artery
UR - http://www.scopus.com/inward/record.url?scp=85091388389&partnerID=8YFLogxK
U2 - 10.3389/fneur.2020.00923
DO - 10.3389/fneur.2020.00923
M3 - Review article
AN - SCOPUS:85091388389
SN - 1664-2295
VL - 11
JO - Frontiers in Neurology
JF - Frontiers in Neurology
M1 - 923
ER -