Microsporidium-associated sinusitis

Ronald B. Moss; Lisa M. Beaudet; Bruce M. Wenig; Ann M. Nelson; Adolfo Firpo; Usha Punja; Thomas S. Scott; Michael A. Kaliner

doi:10.1177/014556139707600209

Microsporidium-associated sinusitis

Ronald B. Moss, Lisa M. Beaudet, Bruce M. Wenig, Ann M. Nelson, Adolfo Firpo, Usha Punja, Thomas S. Scott, Michael A. Kaliner

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Two cases of biopsy-proven Microsporidium-associated chronic sinusitis in HIV-seropositive patients are presented. Spores of Septata intestinalis were identified by light microscopy and confirmed by electron microscopy in each case. Both patients displayed severe deficiencies of nasal mucosa CD4- positive cells, demonstrated by immunohistochemical methods. Only two other cases of Septata intestinalis-associated sinusitis have been reported previously. Our observations agree with the theory that functional defects in local mucosal immunity may partially explain the acquisition of opportunistic mucosal infections in many HIV-seropositive patients.

Original language	English
Pages (from-to)	95-101
Number of pages	7
Journal	Ear, Nose and Throat Journal
Volume	76
Issue number	2
DOIs	https://doi.org/10.1177/014556139707600209
State	Published - Feb 1997
Externally published	Yes

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title = "Microsporidium-associated sinusitis",

abstract = "Two cases of biopsy-proven Microsporidium-associated chronic sinusitis in HIV-seropositive patients are presented. Spores of Septata intestinalis were identified by light microscopy and confirmed by electron microscopy in each case. Both patients displayed severe deficiencies of nasal mucosa CD4- positive cells, demonstrated by immunohistochemical methods. Only two other cases of Septata intestinalis-associated sinusitis have been reported previously. Our observations agree with the theory that functional defects in local mucosal immunity may partially explain the acquisition of opportunistic mucosal infections in many HIV-seropositive patients.",

author = "Moss, {Ronald B.} and Beaudet, {Lisa M.} and Wenig, {Bruce M.} and Nelson, {Ann M.} and Adolfo Firpo and Usha Punja and Scott, {Thomas S.} and Kaliner, {Michael A.}",

year = "1997",

month = feb,

doi = "10.1177/014556139707600209",

language = "English",

volume = "76",

pages = "95--101",

journal = "Ear, Nose and Throat Journal",

issn = "0145-5613",

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TY - JOUR

T1 - Microsporidium-associated sinusitis

AU - Moss, Ronald B.

AU - Beaudet, Lisa M.

AU - Wenig, Bruce M.

AU - Nelson, Ann M.

AU - Firpo, Adolfo

AU - Punja, Usha

AU - Scott, Thomas S.

AU - Kaliner, Michael A.

PY - 1997/2

Y1 - 1997/2

N2 - Two cases of biopsy-proven Microsporidium-associated chronic sinusitis in HIV-seropositive patients are presented. Spores of Septata intestinalis were identified by light microscopy and confirmed by electron microscopy in each case. Both patients displayed severe deficiencies of nasal mucosa CD4- positive cells, demonstrated by immunohistochemical methods. Only two other cases of Septata intestinalis-associated sinusitis have been reported previously. Our observations agree with the theory that functional defects in local mucosal immunity may partially explain the acquisition of opportunistic mucosal infections in many HIV-seropositive patients.

AB - Two cases of biopsy-proven Microsporidium-associated chronic sinusitis in HIV-seropositive patients are presented. Spores of Septata intestinalis were identified by light microscopy and confirmed by electron microscopy in each case. Both patients displayed severe deficiencies of nasal mucosa CD4- positive cells, demonstrated by immunohistochemical methods. Only two other cases of Septata intestinalis-associated sinusitis have been reported previously. Our observations agree with the theory that functional defects in local mucosal immunity may partially explain the acquisition of opportunistic mucosal infections in many HIV-seropositive patients.

UR - http://www.scopus.com/inward/record.url?scp=0031058413&partnerID=8YFLogxK

U2 - 10.1177/014556139707600209

DO - 10.1177/014556139707600209

M3 - Article

C2 - 9046697

AN - SCOPUS:0031058413

SN - 0145-5613

VL - 76

SP - 95

EP - 101

JO - Ear, Nose and Throat Journal

JF - Ear, Nose and Throat Journal

IS - 2

ER -

Microsporidium-associated sinusitis

Abstract

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