TY - JOUR
T1 - Microscopic analysis of the adult Drosophila retina using semithin plastic sections.
AU - Gaengel, Konstantin
AU - Mlodzik, Marek
PY - 2008
Y1 - 2008
N2 - The regular appearance and the repetitive nature of the Drosophila eye, consisting of several hundred identical multicellular units, the ommatidia, has long served as an invaluable experimental system to study cell-cell interactions, inductive signaling events, cell proliferation, programmed cell death, cell differentiation, cell organization, and planar cell polarity among others. Importantly, the eye is dispensable for viability and fertility of the fly and thus, it can easily be manipulated, making it an ideal target for genetic screens. This chapter described an essential technique in the analysis of different genotypes in the adult fly eye, and allows detailed analyses with single cell resolution.
AB - The regular appearance and the repetitive nature of the Drosophila eye, consisting of several hundred identical multicellular units, the ommatidia, has long served as an invaluable experimental system to study cell-cell interactions, inductive signaling events, cell proliferation, programmed cell death, cell differentiation, cell organization, and planar cell polarity among others. Importantly, the eye is dispensable for viability and fertility of the fly and thus, it can easily be manipulated, making it an ideal target for genetic screens. This chapter described an essential technique in the analysis of different genotypes in the adult fly eye, and allows detailed analyses with single cell resolution.
UR - https://www.scopus.com/pages/publications/49649112902
U2 - 10.1007/978-1-59745-583-1_17
DO - 10.1007/978-1-59745-583-1_17
M3 - Article
C2 - 18641954
AN - SCOPUS:49649112902
SN - 1064-3745
VL - 420
SP - 277
EP - 287
JO - Methods in Molecular Biology
JF - Methods in Molecular Biology
ER -