Food allergies have increased in prevalence over the past few decades, particularly among children. In this chapter, we provide a brief overview of the pathogenesis of IgE-mediated food allergies followed by a review of epidemiologic, murine, and human cohort studies that have suggested relationships between microbial communities and the development and course of food allergy. We explore potential mechanisms underlying these findings, and we discuss modalities for microbiome-based therapies for food allergy.

Original languageEnglish
Title of host publicationThe Developing Microbiome
Subtitle of host publicationLessons from Early Life
Number of pages12
ISBN (Electronic)9780128206027
StatePublished - 1 Jan 2020


  • Fecal microbiota transplantation
  • Food allergy
  • Microbiome
  • Microbiota
  • Oral tolerance
  • Prebiotics
  • Probiotics
  • Regulatory T cell
  • Sensitization
  • Synbiotics
  • T helper type 2 (th2
  • Type 2)


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