Abstract
Food allergies have increased in prevalence over the past few decades, particularly among children. In this chapter, we provide a brief overview of the pathogenesis of IgE-mediated food allergies followed by a review of epidemiologic, murine, and human cohort studies that have suggested relationships between microbial communities and the development and course of food allergy. We explore potential mechanisms underlying these findings, and we discuss modalities for microbiome-based therapies for food allergy.
Original language | English |
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Title of host publication | The Developing Microbiome |
Subtitle of host publication | Lessons from Early Life |
Publisher | Elsevier |
Pages | 145-156 |
Number of pages | 12 |
ISBN (Electronic) | 9780128206027 |
DOIs | |
State | Published - 1 Jan 2020 |
Keywords
- Fecal microbiota transplantation
- Food allergy
- Microbiome
- Microbiota
- Oral tolerance
- Prebiotics
- Probiotics
- Regulatory T cell
- Sensitization
- Synbiotics
- T helper type 2 (th2
- Type 2)