TY - JOUR
T1 - Methylphenidate Response in Aggressive and Nonaggressive ADHD Children
T2 - Distinctions on Laboratory Measures of Symptoms
AU - MATIER, KRISTIN
AU - HALPERIN, JEFFREY M.
AU - SHARMA, VANSHDEEP
AU - NEWCORN, JEFFREY H.
AU - SATHAYE, NIRMAL
N1 - Funding Information:
This research was supported in part by a Faculty Scholars Award from the William T. Grant Foundation to Jeffrey M. Halperin and grant RR-07064 to Queens College from the General Research Support Branch, N.J.H.
PY - 1992
Y1 - 1992
N2 - Response to a single, 5-mg dose of methylphenidate was compared in aggressive and nonaggressive attention-deficit hyperactivity disorder (ADHD) children using objective measures of inattention, impulsivity, and activity level. After medication, both ADHD groups had a significant decrease in inattention, whereas impulsivity remained unchanged. Activity level decreased only in the nonaggressive ADHD group. Unmedicated normal controls showed no change on any measure. These results support the hypothesis that aggressive and nonaggressive ADHD children have somewhat different underlying determinants for some of their symptoms. In addition, they suggest that inattention, impulsivity, and overactivity may be mediated by partially distinct neural mechanisms.
AB - Response to a single, 5-mg dose of methylphenidate was compared in aggressive and nonaggressive attention-deficit hyperactivity disorder (ADHD) children using objective measures of inattention, impulsivity, and activity level. After medication, both ADHD groups had a significant decrease in inattention, whereas impulsivity remained unchanged. Activity level decreased only in the nonaggressive ADHD group. Unmedicated normal controls showed no change on any measure. These results support the hypothesis that aggressive and nonaggressive ADHD children have somewhat different underlying determinants for some of their symptoms. In addition, they suggest that inattention, impulsivity, and overactivity may be mediated by partially distinct neural mechanisms.
KW - attention-deficit hyperactivity disorder
KW - hyperactivity
KW - impulsivity
KW - inattention
KW - methylphenidate
UR - https://www.scopus.com/pages/publications/0026600581
U2 - 10.1097/00004583-199203000-00007
DO - 10.1097/00004583-199203000-00007
M3 - Article
C2 - 1564022
AN - SCOPUS:0026600581
SN - 0890-8567
VL - 31
SP - 219
EP - 225
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
IS - 2
ER -