Methylphenidate-Induced Obsessive-Compulsive Symptoms in an Elderly Man

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An 82-year-old man with treatment-resistant depression and early Alzheimer's disease was started on methylphenidate. Significant obsessive-compulsive behavior ensued but diminished over several weeks when methylphenidate was replaced by fluvoxamine. The patient had no prior psychiatric history, but he had a sister with obsessive-compulsive disorder. It appears that methylphenidate precipitated the patient's pathological behavior.

Original languageEnglish
Pages (from-to)612-613
Number of pages2
JournalCNS Spectrums
Issue number8
StatePublished - Aug 2003
Externally publishedYes


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