Methotrexate therapy of metastatic choriocarcinoma

James F. Holland

doi:10.1016/0002-9378(58)90571-4

Methotrexate therapy of metastatic choriocarcinoma

James F. Holland

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A patient with choriocarcinoma extensively metastatic to the lungs (and probably pelvis), with elevated urinary gonadotropin titers, has been treated with Methotrexate. The drug was administered orally in intermittent high-dose courses. Regression of tumor masses and fall of gonadotrophin excretion followed. This experience confirms that reported by Li, Hertz, and Spencer.⁴.

Original language	English
Pages (from-to)	195-199
Number of pages	5
Journal	American Journal of Obstetrics and Gynecology
Volume	75
Issue number	1
DOIs	https://doi.org/10.1016/0002-9378(58)90571-4
State	Published - Jan 1958
Externally published	Yes

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title = "Methotrexate therapy of metastatic choriocarcinoma",

abstract = "A patient with choriocarcinoma extensively metastatic to the lungs (and probably pelvis), with elevated urinary gonadotropin titers, has been treated with Methotrexate. The drug was administered orally in intermittent high-dose courses. Regression of tumor masses and fall of gonadotrophin excretion followed. This experience confirms that reported by Li, Hertz, and Spencer.4.",

author = "Holland, \{James F.\}",

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AU - Holland, James F.

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N2 - A patient with choriocarcinoma extensively metastatic to the lungs (and probably pelvis), with elevated urinary gonadotropin titers, has been treated with Methotrexate. The drug was administered orally in intermittent high-dose courses. Regression of tumor masses and fall of gonadotrophin excretion followed. This experience confirms that reported by Li, Hertz, and Spencer.4.

AB - A patient with choriocarcinoma extensively metastatic to the lungs (and probably pelvis), with elevated urinary gonadotropin titers, has been treated with Methotrexate. The drug was administered orally in intermittent high-dose courses. Regression of tumor masses and fall of gonadotrophin excretion followed. This experience confirms that reported by Li, Hertz, and Spencer.4.

UR - https://www.scopus.com/pages/publications/49749210989

U2 - 10.1016/0002-9378(58)90571-4

DO - 10.1016/0002-9378(58)90571-4

M3 - Article

C2 - 13487702

AN - SCOPUS:49749210989

SN - 0002-9378

VL - 75

SP - 195

EP - 199

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

IS - 1

ER -

Methotrexate therapy of metastatic choriocarcinoma

Abstract

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