Metabolomics, Proteomics, and Genomics: An Introduction to a Clinician

Zhe Wang; Bing Yu

doi:10.1016/B978-0-323-54835-9.00015-6

Metabolomics, Proteomics, and Genomics: An Introduction to a Clinician

Zhe Wang
, Bing Yu

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. The molecular etiology of CVD remains incompletely understood. Advances in omics technologies, together with improved annotations, allow for the in-depth analysis of multiomics measures on CVD to identify novel biomarkers and pathways. Here we introduce innovative technologies of proteomics and metabolomics and outline current insights of proteomics and metabolomics on CVD, as well as their interplay with genomics. Taken together, the integration of genomics, proteomics, and metabolomics in a systematic and comprehensive approach holds the potential for elucidating novel CVD biology mechanisms.

Original language	English
Title of host publication	Biomarkers in Cardiovascular Disease
Publisher	Elsevier
Pages	159-170
Number of pages	12
ISBN (Electronic)	9780323548359
DOIs	https://doi.org/10.1016/B978-0-323-54835-9.00015-6
State	Published - 1 Jan 2018
Externally published	Yes

Keywords

Genomics
Metabolomics
cardiovascular disease
omics
proteomics

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10.1016/B978-0-323-54835-9.00015-6

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title = "Metabolomics, Proteomics, and Genomics: An Introduction to a Clinician",

abstract = "Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. The molecular etiology of CVD remains incompletely understood. Advances in omics technologies, together with improved annotations, allow for the in-depth analysis of multiomics measures on CVD to identify novel biomarkers and pathways. Here we introduce innovative technologies of proteomics and metabolomics and outline current insights of proteomics and metabolomics on CVD, as well as their interplay with genomics. Taken together, the integration of genomics, proteomics, and metabolomics in a systematic and comprehensive approach holds the potential for elucidating novel CVD biology mechanisms.",

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T2 - An Introduction to a Clinician

AU - Wang, Zhe

AU - Yu, Bing

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N2 - Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. The molecular etiology of CVD remains incompletely understood. Advances in omics technologies, together with improved annotations, allow for the in-depth analysis of multiomics measures on CVD to identify novel biomarkers and pathways. Here we introduce innovative technologies of proteomics and metabolomics and outline current insights of proteomics and metabolomics on CVD, as well as their interplay with genomics. Taken together, the integration of genomics, proteomics, and metabolomics in a systematic and comprehensive approach holds the potential for elucidating novel CVD biology mechanisms.

AB - Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. The molecular etiology of CVD remains incompletely understood. Advances in omics technologies, together with improved annotations, allow for the in-depth analysis of multiomics measures on CVD to identify novel biomarkers and pathways. Here we introduce innovative technologies of proteomics and metabolomics and outline current insights of proteomics and metabolomics on CVD, as well as their interplay with genomics. Taken together, the integration of genomics, proteomics, and metabolomics in a systematic and comprehensive approach holds the potential for elucidating novel CVD biology mechanisms.

KW - Genomics

KW - Metabolomics

KW - cardiovascular disease

KW - omics

KW - proteomics

UR - https://www.scopus.com/pages/publications/85123660408

U2 - 10.1016/B978-0-323-54835-9.00015-6

DO - 10.1016/B978-0-323-54835-9.00015-6

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SP - 159

EP - 170

BT - Biomarkers in Cardiovascular Disease

PB - Elsevier

ER -

Metabolomics, Proteomics, and Genomics: An Introduction to a Clinician

Abstract

Keywords

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