@inbook{b6a3f28045354dbf826fbbcd60127f30,
title = "Metabolic relationship between cancer-associated fibroblasts and cancer cells",
abstract = "Cancer-associated fibroblasts undergo the reverse Warburg effect and provide cancer cells with glycolytic metabolites.The interaction between cancer cells and CAFs helps cancer cells manage the Warburg effect.Loss of stromal Cav-1 is a biomarker of poor prognosis in breast cancers.CAF-derived exosomes (CDE) can reprogram the metabolic pathway of cancer cells.CAFs augment cancer addiction to glutamine and its metabolically-relevant consequences.Alanine secreted by pancreatic stellate cells supports tumor metabolism.",
keywords = "CAF-derived exosomes, Cancer-associated fibroblasts, Glutamine metabolism, Hypoxia-inducible factor-1, Reverse Warburg effect",
author = "Christos Sazeides and Anne Le",
note = "Publisher Copyright: {\textcopyright} 2018, Springer International Publishing AG, part of Springer Nature.",
year = "2018",
doi = "10.1007/978-3-319-77736-8_11",
language = "English",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "149--165",
booktitle = "Advances in Experimental Medicine and Biology",
}