Mesenchymal stem cells in the infarcted heart

Mohit Jain; Otmar Pfister; Roger J. Hajjar; Ronglih Liao

doi:10.1097/00019501-200503000-00003

Mesenchymal stem cells in the infarcted heart

Mohit Jain, Otmar Pfister, Roger J. Hajjar, Ronglih Liao

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

A loss of functional cardiomyocytes forms the cellular basis of cardiac dysfunction and heart failure. Stem cell based repletion of scarred myocardial tissue and regeneration of cardiomyocytes have been proposed as a potential treatment of ventricular dysfunction. In this review, we provide an overview of recent studies utilizing mesenchymal stem cells in cardiac regeneration and post-myocardial infarct therapy.

Original language	English
Pages (from-to)	93-97
Number of pages	5
Journal	Coronary Artery Disease
Volume	16
Issue number	2
DOIs	https://doi.org/10.1097/00019501-200503000-00003
State	Published - Mar 2005
Externally published	Yes

Keywords

Cell therapy
Mesenchymal stem cells
Myocardial infarction
Myocardial regeneration

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10.1097/00019501-200503000-00003

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abstract = "A loss of functional cardiomyocytes forms the cellular basis of cardiac dysfunction and heart failure. Stem cell based repletion of scarred myocardial tissue and regeneration of cardiomyocytes have been proposed as a potential treatment of ventricular dysfunction. In this review, we provide an overview of recent studies utilizing mesenchymal stem cells in cardiac regeneration and post-myocardial infarct therapy.",

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author = "Mohit Jain and Otmar Pfister and Hajjar, {Roger J.} and Ronglih Liao",

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AU - Pfister, Otmar

AU - Hajjar, Roger J.

AU - Liao, Ronglih

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N2 - A loss of functional cardiomyocytes forms the cellular basis of cardiac dysfunction and heart failure. Stem cell based repletion of scarred myocardial tissue and regeneration of cardiomyocytes have been proposed as a potential treatment of ventricular dysfunction. In this review, we provide an overview of recent studies utilizing mesenchymal stem cells in cardiac regeneration and post-myocardial infarct therapy.

AB - A loss of functional cardiomyocytes forms the cellular basis of cardiac dysfunction and heart failure. Stem cell based repletion of scarred myocardial tissue and regeneration of cardiomyocytes have been proposed as a potential treatment of ventricular dysfunction. In this review, we provide an overview of recent studies utilizing mesenchymal stem cells in cardiac regeneration and post-myocardial infarct therapy.

KW - Cell therapy

KW - Mesenchymal stem cells

KW - Myocardial infarction

KW - Myocardial regeneration

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Mesenchymal stem cells in the infarcted heart

Abstract

Keywords

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