@article{b3d2fce5e3134ebfa69585e1472b12c4,
title = "Meiotic chromosomal changes and sterility produced by nitrogen mustard and procarbazine in mice",
abstract = "Treatment and survival of reproductive-age patients with chemotherapy raises the question of possible effects on procreative ability. An attempt has been made to establish an animal model system. The anticancer agents nitrogen mustard and procarbazine caused decreased fertility in mice of both sexes and induced meiotic chromosomal abnormalities, at least in the male. Progeny of treated mice showed similar meiotic chromosomal changes. The possibility of similar effects in human beings receiving chemotherapy must be considered.",
author = "Chryssanthou, {C. P.} and Wallach, {R. C.} and M. Atchison",
note = "Funding Information: Received March 23, 1982; revised and accepted August 4, 1982. *Supported in part by the Lenore Weinstein Fund. tDepartment of Pathology, Beth Israel Medical Center and Mount Sinai School of Medicine. :/:Reprint requests: Dr. Chryssanthos P. Chryssanthou, Department of Pathology, Beth Israel Medical Center, 10 Nathan D. Perlman Place, New York, New York 10003. §Department of Obstetrics and Gynecology, Beth Israel Medical Center and Mount Sinai School of Medicine. [[Institute of Environmental Medicine, New York University Medical Center.",
year = "1983",
doi = "10.1016/s0015-0282(16)46765-8",
language = "English",
volume = "39",
pages = "97--102",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "1",
}