Medical Management of LPR

Justin Field; Deena Midani; Yellowlees Douglas; Michael S. Smith

doi:10.1007/978-3-030-12318-5_5

Medical Management of LPR

Justin Field, Deena Midani, Yellowlees Douglas, Michael S. Smith

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Laryngopharyngeal reflux (LPR) is a disorder that may cause a variety of symptoms, including dysphagia, chronic cough, postnasal drip, hoarseness, and fatigue. These symptoms stem from gastroesophageal reflux disease (GERD), which is far more widely studied and also offers multiple treatment modalities compared to the understudied LPR. These approaches prove particularly relevant for patients who have failed lifestyle modifications and include pharmacotherapy ranging from proton-pump inhibitors and histamine-2 receptor antagonists to GABAB agonists and neuromodulators. In addition, relatively new and minimally invasive endoscopic techniques for addressing LPR include transoral incisionless fundoplication, radiofrequency ablation of the lower esophageal sphincter, and anterior fundoplication, any of which may provide patients with relief from symptoms of LPR.

Original language	English
Title of host publication	Laryngopharyngeal Reflux Disease
Subtitle of host publication	Integrative Approaches
Publisher	Springer International Publishing
Pages	59-73
Number of pages	15
ISBN (Electronic)	9783030123185
ISBN (Print)	9783030123178
DOIs	https://doi.org/10.1007/978-3-030-12318-5_5
State	Published - 1 Jan 2019
Externally published	Yes

Keywords

Endoscopic fundoplication
Gastroesophageal reflux disease
Laryngopharyngeal reflux
Neuromodulators
Prokinetics
Proton-pump inhibitors

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10.1007/978-3-030-12318-5_5

Cite this

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title = "Medical Management of LPR",

abstract = "Laryngopharyngeal reflux (LPR) is a disorder that may cause a variety of symptoms, including dysphagia, chronic cough, postnasal drip, hoarseness, and fatigue. These symptoms stem from gastroesophageal reflux disease (GERD), which is far more widely studied and also offers multiple treatment modalities compared to the understudied LPR. These approaches prove particularly relevant for patients who have failed lifestyle modifications and include pharmacotherapy ranging from proton-pump inhibitors and histamine-2 receptor antagonists to GABAB agonists and neuromodulators. In addition, relatively new and minimally invasive endoscopic techniques for addressing LPR include transoral incisionless fundoplication, radiofrequency ablation of the lower esophageal sphincter, and anterior fundoplication, any of which may provide patients with relief from symptoms of LPR.",

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AU - Midani, Deena

AU - Douglas, Yellowlees

AU - Smith, Michael S.

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N2 - Laryngopharyngeal reflux (LPR) is a disorder that may cause a variety of symptoms, including dysphagia, chronic cough, postnasal drip, hoarseness, and fatigue. These symptoms stem from gastroesophageal reflux disease (GERD), which is far more widely studied and also offers multiple treatment modalities compared to the understudied LPR. These approaches prove particularly relevant for patients who have failed lifestyle modifications and include pharmacotherapy ranging from proton-pump inhibitors and histamine-2 receptor antagonists to GABAB agonists and neuromodulators. In addition, relatively new and minimally invasive endoscopic techniques for addressing LPR include transoral incisionless fundoplication, radiofrequency ablation of the lower esophageal sphincter, and anterior fundoplication, any of which may provide patients with relief from symptoms of LPR.

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Medical Management of LPR

Abstract

Keywords

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