Medical and Surgical Treatments of Tourette Syndrome

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Tourette syndrome is a complex neuropsychiatric disorder with a wide phenotypic spectrum, including tics and psychiatric comorbidities, such as obsessive-compulsive disorder and attention-deficit disorder. Often considered a neurodevelopmental disorder, it is most prevalent during childhood and treatment strategies can vary according to degree of severity and patient-specific symptom manifestations. This review focuses on established and emerging management options for tics, including behavioral interventions and nonpharmacologic therapies, medication management, and promising surgical approaches.

Original languageEnglish
Pages (from-to)349-366
Number of pages18
JournalNeurologic Clinics
Issue number2
StatePublished - May 2020


  • Alpha-2 agonists
  • Cognitive behavioral intervention for tics (CBIT)
  • Deep brain stimulation
  • Dopamine receptor blocking drugs
  • Tics
  • Tourette syndrome
  • Vesicular monoamine transporter type 2 inhibitors


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