Mechanisms regulating lymphocytic infiltration of the thyroid in murine models of thyroiditis

Sergio A. Lira; Andrea P. Martin; Tatjana Marinkovic; Glaucia C. Furtado

doi:10.1615/CritRevImmunol.v25.i4.10

Mechanisms regulating lymphocytic infiltration of the thyroid in murine models of thyroiditis

Sergio A. Lira, Andrea P. Martin, Tatjana Marinkovic, Glaucia C. Furtado

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Abstract

The autoimmune diseases of the thyroid are the most prevalent autoimmune diseases in man. In these diseases, the thyroid is invariably infiltrated by lymphocytes, which play a major role in pathogenesis. In this review, we discuss the mechanisms associated with lymphocytic infiltration of the thyroid, examining different models of thyroid autoimmune disease in mice.

Original language	English
Pages (from-to)	251-262
Number of pages	12
Journal	Critical Reviews in Immunology
Volume	25
Issue number	4
DOIs	https://doi.org/10.1615/CritRevImmunol.v25.i4.10
State	Published - 2005

Keywords

Autoimmunity
Chemokines
Cytokines
Models
Thyroid
Transgenic mice

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10.1615/CritRevImmunol.v25.i4.10

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abstract = "The autoimmune diseases of the thyroid are the most prevalent autoimmune diseases in man. In these diseases, the thyroid is invariably infiltrated by lymphocytes, which play a major role in pathogenesis. In this review, we discuss the mechanisms associated with lymphocytic infiltration of the thyroid, examining different models of thyroid autoimmune disease in mice.",

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KW - Cytokines

KW - Models

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KW - Transgenic mice

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Mechanisms regulating lymphocytic infiltration of the thyroid in murine models of thyroiditis

Abstract

Keywords

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