TY - JOUR
T1 - Mechanisms of Unstable Angina
AU - Fuster, Valentin
AU - Chesebro, James H.
PY - 1986/10/16
Y1 - 1986/10/16
N2 - The hallmark of unstable angina is its unpredictability. The symptoms, which occur without provocation, sometimes stabilize or resolve but sometimes progress to myocardial infarction or sudden death. This pattern contrasts with that of stable angina. Early data suggested that transient increases in myocardial oxygen demand might explain episodes of pain that occurred at rest in patients with unstable angina.1 In the late 1970s, however, clinical, electrocardiographic, radionuclide, and myocardial bloodflow studies suggested that episodes of myocardial ischemia and pain at rest were the result of abrupt reductions in coronary blood flow. The emphasis had changed from the demand to the.
AB - The hallmark of unstable angina is its unpredictability. The symptoms, which occur without provocation, sometimes stabilize or resolve but sometimes progress to myocardial infarction or sudden death. This pattern contrasts with that of stable angina. Early data suggested that transient increases in myocardial oxygen demand might explain episodes of pain that occurred at rest in patients with unstable angina.1 In the late 1970s, however, clinical, electrocardiographic, radionuclide, and myocardial bloodflow studies suggested that episodes of myocardial ischemia and pain at rest were the result of abrupt reductions in coronary blood flow. The emphasis had changed from the demand to the.
UR - http://www.scopus.com/inward/record.url?scp=0022479678&partnerID=8YFLogxK
U2 - 10.1056/NEJM198610163151608
DO - 10.1056/NEJM198610163151608
M3 - Editorial
C2 - 3531856
AN - SCOPUS:0022479678
SN - 0028-4793
VL - 315
SP - 1023
EP - 1025
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 16
ER -