Mechanism of disturbances of energy formation in acute ischemia of the liver

I. V. Levandovskii; V. V. Lyakhovich; A. V. Panov; V. N. Solov'ev; I. B. Tsyrlov; T. M. Oksman

doi:10.1007/BF00805882

Mechanism of disturbances of energy formation in acute ischemia of the liver

I. V. Levandovskii, V. V. Lyakhovich, A. V. Panov, V. N. Solov'ev, I. B. Tsyrlov, T. M. Oksman

Research output: Contribution to journal › Article › peer-review

Abstract

Respiration of rat liver mitochondria after the addition of ischemic toxin to the incubation medium was compared with respiration of mitochondria isolated from ischemic rat liver. The changes in respiration in both cases could be prevented by preliminary addition of dithiothreitol and reduced by subsequent addition of cytochrome c or dithiothreitol to the incubation medium. The similarity between the mechanisms of disturbance of energy formation is postulated.

Original language	English
Pages (from-to)	1274-1276
Number of pages	3
Journal	Bulletin of Experimental Biology and Medicine
Volume	84
Issue number	3
DOIs	https://doi.org/10.1007/BF00805882
State	Published - Sep 1977

Keywords

cytochrome c
dithiothreitol
ischemia of the liver
ischemic toxin
mitochondria

Access to Document

10.1007/BF00805882

Cite this

@article{77a30d53b8c24d8c98e83b624a800581,

title = "Mechanism of disturbances of energy formation in acute ischemia of the liver",

abstract = "Respiration of rat liver mitochondria after the addition of ischemic toxin to the incubation medium was compared with respiration of mitochondria isolated from ischemic rat liver. The changes in respiration in both cases could be prevented by preliminary addition of dithiothreitol and reduced by subsequent addition of cytochrome c or dithiothreitol to the incubation medium. The similarity between the mechanisms of disturbance of energy formation is postulated.",

keywords = "cytochrome c, dithiothreitol, ischemia of the liver, ischemic toxin, mitochondria",

author = "Levandovskii, {I. V.} and Lyakhovich, {V. V.} and Panov, {A. V.} and Solov'ev, {V. N.} and Tsyrlov, {I. B.} and Oksman, {T. M.}",

year = "1977",

month = sep,

doi = "10.1007/BF00805882",

language = "English",

volume = "84",

pages = "1274--1276",

journal = "Bulletin of Experimental Biology and Medicine",

issn = "0007-4888",

publisher = "Springer",

number = "3",

}

TY - JOUR

T1 - Mechanism of disturbances of energy formation in acute ischemia of the liver

AU - Levandovskii, I. V.

AU - Lyakhovich, V. V.

AU - Panov, A. V.

AU - Solov'ev, V. N.

AU - Tsyrlov, I. B.

AU - Oksman, T. M.

PY - 1977/9

Y1 - 1977/9

N2 - Respiration of rat liver mitochondria after the addition of ischemic toxin to the incubation medium was compared with respiration of mitochondria isolated from ischemic rat liver. The changes in respiration in both cases could be prevented by preliminary addition of dithiothreitol and reduced by subsequent addition of cytochrome c or dithiothreitol to the incubation medium. The similarity between the mechanisms of disturbance of energy formation is postulated.

AB - Respiration of rat liver mitochondria after the addition of ischemic toxin to the incubation medium was compared with respiration of mitochondria isolated from ischemic rat liver. The changes in respiration in both cases could be prevented by preliminary addition of dithiothreitol and reduced by subsequent addition of cytochrome c or dithiothreitol to the incubation medium. The similarity between the mechanisms of disturbance of energy formation is postulated.

KW - cytochrome c

KW - dithiothreitol

KW - ischemia of the liver

KW - ischemic toxin

KW - mitochondria

UR - http://www.scopus.com/inward/record.url?scp=0017799672&partnerID=8YFLogxK

U2 - 10.1007/BF00805882

DO - 10.1007/BF00805882

M3 - Article

AN - SCOPUS:0017799672

SN - 0007-4888

VL - 84

SP - 1274

EP - 1276

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

IS - 3

ER -

Mechanism of disturbances of energy formation in acute ischemia of the liver

Abstract

Keywords

Access to Document

Fingerprint

Cite this