TY - GEN
T1 - MECHANICAL STRAIN ENVIRONMENT CONTROLS NEW BONE FORMATION DURING DISTRACTION OSTEOGENESIS
AU - Richards, Mark
AU - Weiss, Jeffrey A.
AU - Alsberg, Eben
AU - Shibuya, Takaaki
AU - Schaffler, Mitchell B.
AU - Goldstein, Steven A.
AU - Goulet, Janies A.
N1 - Publisher Copyright:
© 1996 American Society of Mechanical Engineers (ASME). All rights reserved.
PY - 1996
Y1 - 1996
N2 - An animal model of distraction osteogenesis was used to investigate the effects of altered stresses and strains on tissue development, differentiation, and repair. Osteotomies were performed at 0 and 45 degrees to create different mechanical environments within the distraction gap. Finite element simulations of functional loading and actual distractions indicated significant changes in the gap deformation field. These differences correlated with significant decreases in new bone volume and changes in trabecular architecture for the 45-degree case.
AB - An animal model of distraction osteogenesis was used to investigate the effects of altered stresses and strains on tissue development, differentiation, and repair. Osteotomies were performed at 0 and 45 degrees to create different mechanical environments within the distraction gap. Finite element simulations of functional loading and actual distractions indicated significant changes in the gap deformation field. These differences correlated with significant decreases in new bone volume and changes in trabecular architecture for the 45-degree case.
UR - https://www.scopus.com/pages/publications/85169298654
U2 - 10.1115/IMECE1996-1272
DO - 10.1115/IMECE1996-1272
M3 - Conference contribution
AN - SCOPUS:85169298654
T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
SP - 377
EP - 378
BT - Advances in Bioengineering
PB - American Society of Mechanical Engineers (ASME)
T2 - ASME 1996 International Mechanical Engineering Congress and Exposition, IMECE 1996
Y2 - 17 November 1996 through 22 November 1996
ER -