MDS mit Deletion 5q- Eine Sonderform myelodysplastischer Syndrome

Christian Matthias Wilk; Jeroen Simon Goede

doi:10.1024/0040-5930/a001333

MDS mit Deletion 5q- Eine Sonderform myelodysplastischer Syndrome

Translated title of the contribution: MDS with deletion 5q - A distinct subtype of myelodysplastic syndromes

Christian Matthias Wilk
, Jeroen Simon Goede

Research output: Contribution to journal › Article › peer-review

Abstract

Deletion of the long arm of chromosome 5 (del(5q)) is a recurrent anomaly in myelodysplastic syndromes associated with a distinct pathophysiology and specific treatment options. MDS with isolated del(5q) are associated with a favorable risk profile and can be treated with lenalidomide. MDS with isolated del(q) have to be distinguished from MDS with an anomaly on the long arm of chromosome 5 and more than one additional mutation turning these cases into high-risk forms of MDS.

Translated title of the contribution	MDS with deletion 5q - A distinct subtype of myelodysplastic syndromes
Original language	German
Pages (from-to)	87-91
Number of pages	5
Journal	Therapeutische Umschau. Revue therapeutique
Volume	79
Issue number	2
DOIs	https://doi.org/10.1024/0040-5930/a001333
State	Published - Mar 2022
Externally published	Yes

Access to Document

10.1024/0040-5930/a001333

Cite this

@article{84c470e6d3dd484883e0a9e4ecc6d2d9,

title = "MDS mit Deletion 5q- Eine Sonderform myelodysplastischer Syndrome",

abstract = "Deletion of the long arm of chromosome 5 (del(5q)) is a recurrent anomaly in myelodysplastic syndromes associated with a distinct pathophysiology and specific treatment options. MDS with isolated del(5q) are associated with a favorable risk profile and can be treated with lenalidomide. MDS with isolated del(q) have to be distinguished from MDS with an anomaly on the long arm of chromosome 5 and more than one additional mutation turning these cases into high-risk forms of MDS.",

author = "Wilk, \{Christian Matthias\} and Goede, \{Jeroen Simon\}",

note = "Publisher Copyright: {\textcopyright} 2022 Hogrefe AG.",

year = "2022",

month = mar,

doi = "10.1024/0040-5930/a001333",

language = "German",

volume = "79",

pages = "87--91",

journal = "Therapeutische Umschau. Revue therapeutique",

issn = "0040-5930",

publisher = "Hogrefe Publishing",

number = "2",

}

TY - JOUR

T1 - MDS mit Deletion 5q- Eine Sonderform myelodysplastischer Syndrome

AU - Wilk, Christian Matthias

AU - Goede, Jeroen Simon

PY - 2022/3

Y1 - 2022/3

N2 - Deletion of the long arm of chromosome 5 (del(5q)) is a recurrent anomaly in myelodysplastic syndromes associated with a distinct pathophysiology and specific treatment options. MDS with isolated del(5q) are associated with a favorable risk profile and can be treated with lenalidomide. MDS with isolated del(q) have to be distinguished from MDS with an anomaly on the long arm of chromosome 5 and more than one additional mutation turning these cases into high-risk forms of MDS.

AB - Deletion of the long arm of chromosome 5 (del(5q)) is a recurrent anomaly in myelodysplastic syndromes associated with a distinct pathophysiology and specific treatment options. MDS with isolated del(5q) are associated with a favorable risk profile and can be treated with lenalidomide. MDS with isolated del(q) have to be distinguished from MDS with an anomaly on the long arm of chromosome 5 and more than one additional mutation turning these cases into high-risk forms of MDS.

UR - https://www.scopus.com/pages/publications/85127365961

U2 - 10.1024/0040-5930/a001333

DO - 10.1024/0040-5930/a001333

M3 - Article

AN - SCOPUS:85127365961

SN - 0040-5930

VL - 79

SP - 87

EP - 91

JO - Therapeutische Umschau. Revue therapeutique

JF - Therapeutische Umschau. Revue therapeutique

IS - 2

ER -

MDS mit Deletion 5q- Eine Sonderform myelodysplastischer Syndrome

Abstract

Access to Document

Fingerprint

Cite this