McLeod syndrome

R. H. Walker

doi:10.1016/B978-0-12-809324-5.00665-9

McLeod syndrome

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

McLeod syndrome is a rare X-linked recessive neuroacanthocytosis syndrome, caused by mutations of the gene encoding for the McLeod protein XK. Symptoms include chorea and other movement disorders, and several other peripheral and central neurological abnormalities. Cardiomyopathy and hepatosplenomegaly are typical. Psychiatric and cognitive impairment may be seen. Elevated creatine kinase and liver enzyme abnormalities suggest the diagnosis.

Original language	English
Title of host publication	The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Publisher	Elsevier Science Ltd.
Pages	162-164
Number of pages	3
ISBN (Electronic)	9780128093245
DOIs	https://doi.org/10.1016/B978-0-12-809324-5.00665-9
State	Published - 1 Jan 2016

Keywords

Acanthocytosis
Cardiomyopathy
Chorea
Erythrocyte
McLeod syndrome
Neuroacanthocytosis
Neuropathy
Seizures
XK

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10.1016/B978-0-12-809324-5.00665-9

Cite this

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AB - McLeod syndrome is a rare X-linked recessive neuroacanthocytosis syndrome, caused by mutations of the gene encoding for the McLeod protein XK. Symptoms include chorea and other movement disorders, and several other peripheral and central neurological abnormalities. Cardiomyopathy and hepatosplenomegaly are typical. Psychiatric and cognitive impairment may be seen. Elevated creatine kinase and liver enzyme abnormalities suggest the diagnosis.

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KW - Cardiomyopathy

KW - Chorea

KW - Erythrocyte

KW - McLeod syndrome

KW - Neuroacanthocytosis

KW - Neuropathy

KW - Seizures

KW - XK

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BT - The Curated Reference Collection in Neuroscience and Biobehavioral Psychology

PB - Elsevier Science Ltd.

ER -

McLeod syndrome

Abstract

Keywords

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