Mazindol treatment for cocaine dependence

Susan M. Stine; John H. Krystal; Thomas R. Kosten; Dennis S. Charney

doi:10.1016/0376-8716(95)01174-4

Mazindol treatment for cocaine dependence

Susan M. Stine, John H. Krystal, Thomas R. Kosten, Dennis S. Charney

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-report of times used, dollars spent, craving, etc.) measures. There was no response difference between patients treated with mazindol and those who received placebo.

Original language	English
Pages (from-to)	245-252
Number of pages	8
Journal	Drug and Alcohol Dependence
Volume	39
Issue number	3
DOIs	https://doi.org/10.1016/0376-8716(95)01174-4
State	Published - Oct 1995
Externally published	Yes

Keywords

Cocaine abuse
Mazindol
Treatment

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10.1016/0376-8716(95)01174-4

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title = "Mazindol treatment for cocaine dependence",

abstract = "This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-report of times used, dollars spent, craving, etc.) measures. There was no response difference between patients treated with mazindol and those who received placebo.",

keywords = "Cocaine abuse, Mazindol, Treatment",

author = "Stine, {Susan M.} and Krystal, {John H.} and Kosten, {Thomas R.} and Charney, {Dennis S.}",

year = "1995",

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AU - Stine, Susan M.

AU - Krystal, John H.

AU - Kosten, Thomas R.

AU - Charney, Dennis S.

PY - 1995/10

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AB - This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-report of times used, dollars spent, craving, etc.) measures. There was no response difference between patients treated with mazindol and those who received placebo.

KW - Cocaine abuse

KW - Mazindol

KW - Treatment

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U2 - 10.1016/0376-8716(95)01174-4

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JO - Drug and Alcohol Dependence

JF - Drug and Alcohol Dependence

IS - 3

ER -

Mazindol treatment for cocaine dependence

Abstract

Keywords

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