TY - JOUR
T1 - Maximum home blood pressure readings are associated with left atrial diameter in essential hypertensives
AU - Kaihara, Toshiki
AU - Imaizumi, Yuki
AU - Eguchi, Kazuo
AU - Kario, Kazuomi
N1 - Publisher Copyright:
© 2018 Macmillan Publishers Limited, part of Springer Nature.
PY - 2018/6/1
Y1 - 2018/6/1
N2 - We tested the hypothesis that the maximum value of home systolic BP (MSBP) is a marker of hypertensive target organ damage (TOD). We conducted a cross-sectional study of 220 hypertensives. The subjects performed HBP monitoring using a telemonitoring system and measured their HBP for 7 days. Mean, maximum, standard deviation, and coefficient of variation of SBPs were used as independent variables. Brachial-ankle pulse wave velocity, left ventricular mass index (LVMI), mean carotid intima-media thickness, and left atrial diameter index (LADI) were used as dependent variables. Mean and maximum SBPs were significantly associated with each TOD marker. MSBP showed a significantly stronger association with LADI compared to mean SBP (p = 0.0012) and a significant relationship with LADI independent of LVMI (p = 0.024). Our findings suggest that MSBP is associated with TOD measures, similar to mean SBP. These results may indicate that MSBP could be a target of intervention for patients with atrial fibrillation.
AB - We tested the hypothesis that the maximum value of home systolic BP (MSBP) is a marker of hypertensive target organ damage (TOD). We conducted a cross-sectional study of 220 hypertensives. The subjects performed HBP monitoring using a telemonitoring system and measured their HBP for 7 days. Mean, maximum, standard deviation, and coefficient of variation of SBPs were used as independent variables. Brachial-ankle pulse wave velocity, left ventricular mass index (LVMI), mean carotid intima-media thickness, and left atrial diameter index (LADI) were used as dependent variables. Mean and maximum SBPs were significantly associated with each TOD marker. MSBP showed a significantly stronger association with LADI compared to mean SBP (p = 0.0012) and a significant relationship with LADI independent of LVMI (p = 0.024). Our findings suggest that MSBP is associated with TOD measures, similar to mean SBP. These results may indicate that MSBP could be a target of intervention for patients with atrial fibrillation.
UR - http://www.scopus.com/inward/record.url?scp=85046074695&partnerID=8YFLogxK
U2 - 10.1038/s41371-018-0060-3
DO - 10.1038/s41371-018-0060-3
M3 - Article
C2 - 29713049
AN - SCOPUS:85046074695
SN - 0950-9240
VL - 32
SP - 432
EP - 439
JO - Journal of Human Hypertension
JF - Journal of Human Hypertension
IS - 6
ER -