TY - JOUR
T1 - Mathematical modelling of pulsed magnetic field action on neurons' bioelectric activity
AU - Rezinkina, Marina
AU - Markov, Marko
PY - 2009/6
Y1 - 2009/6
N2 - Hodgkin-Huxley model, describing generation of action potentials in axons' membranes, has been used for appreciation of the possible mechanisms of electromagnetic fields influence on neurons' electrical activity. It follows from the carried calculations that flowing through an axon of the external current pulses, which have an area of rise, an area of DC, and an area of drop, does not influence own excitation pulses passage if periods of rise and drop are slope enough. Depending on the external current parameters, own excitation pulses may not be influenced or may be suppressed at greater velocity of rise and drop of an external current. Moreover, induced excitation pulses appear at definite parameters of an external current. In the case, when at passage through an axon of an external current, own excitation pulses follow one by one (paired pulse facilitation), and the second pulse may be suppressed if its level will not be increased additionally in comparison with the case of an external current absence. It is possible that such increase happens "automatically" as a result of "tuning" (adaptation) of axons to the conditions of flowing through them of an external current. It may be an explanation of the phenomena observed in experiments.
AB - Hodgkin-Huxley model, describing generation of action potentials in axons' membranes, has been used for appreciation of the possible mechanisms of electromagnetic fields influence on neurons' electrical activity. It follows from the carried calculations that flowing through an axon of the external current pulses, which have an area of rise, an area of DC, and an area of drop, does not influence own excitation pulses passage if periods of rise and drop are slope enough. Depending on the external current parameters, own excitation pulses may not be influenced or may be suppressed at greater velocity of rise and drop of an external current. Moreover, induced excitation pulses appear at definite parameters of an external current. In the case, when at passage through an axon of an external current, own excitation pulses follow one by one (paired pulse facilitation), and the second pulse may be suppressed if its level will not be increased additionally in comparison with the case of an external current absence. It is possible that such increase happens "automatically" as a result of "tuning" (adaptation) of axons to the conditions of flowing through them of an external current. It may be an explanation of the phenomena observed in experiments.
UR - https://www.scopus.com/pages/publications/63349112871
U2 - 10.1007/s10669-008-9200-6
DO - 10.1007/s10669-008-9200-6
M3 - Article
AN - SCOPUS:63349112871
SN - 0251-1088
VL - 29
SP - 147
EP - 152
JO - Environmentalist
JF - Environmentalist
IS - 2 SPEC. ISS.
ER -