Maternal and neonatal outcomes after delayed-interval delivery of multifetal pregnancies

Ashley S. Roman, Shira Fishman, Nathan Fox, Chad Klauser, Daniel Saltzman, Andrei Rebarber

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


The objective of this study is to evaluate neonatal and maternal outcomes of multiple gestations undergoing delayed-interval delivery at a single institution. A 10-year retrospective review of medical records of patients followed by a Maternal-Fetal Medicine practice in a university-based setting was performed. Patients met criteria for inclusion if a single fetus was delivered spontaneously between 16 and 28 weeks of gestation and a planned attempt was made to prolong the gestation for the remaining fetus(es). Nineteen pregnancies met criteria for inclusion. The median gestational age at delivery of the first fetus was 20 2/7weeks. The median latency was 16 days (range 0 to 152 days). Three patients (15.8%) delivered within 24 hours. There was a 15.8% survival rate for the firstborn fetus and a 53.8% survival rate for all retained fetuses (p = 0.01). There was a 31.6% incidence of serious maternal morbidity related to the procedure. One patient required a postpartum hysterectomy due to massive hemorrhage and uterine atony. Delayed-interval delivery is associated with a higher neonatal survival rate when retained fetuses are compared with firstborn fetuses. However, the procedure is associated with a significant risk of serious maternal morbidity.

Original languageEnglish
Pages (from-to)91-95
Number of pages5
JournalAmerican Journal of Perinatology
Issue number2
StatePublished - 2011
Externally publishedYes


  • Multifetal pregnancy
  • delayed-interval delivery
  • maternal morbidity
  • neonatal morbidity


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