Abstract
Maraviroc was synthesized by Pfizer as UK-427,857 (4, 4- difluoro-N-[(1S)-3-[exo-3-(3-isopropyl-5-methyl-4H-1,2,4- triazol-4-yl)-8-azabi-cyclo[3.2.1]oct-8-yl]-1-phenylpropyl] cyclohexanecarboxamide) (Dorr et al., 2005; Wood and Armour, 2005). The molecular weight of maraviroc is 514, and its chemical structure is shown in Figure 253.1.
Original language | English |
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Title of host publication | Kucers the Use of Antibiotics |
Subtitle of host publication | A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs, Seventh Edition |
Publisher | CRC Press |
Pages | 4307-4320 |
Number of pages | 14 |
ISBN (Electronic) | 9781498747967 |
ISBN (Print) | 9781498747950 |
DOIs | |
State | Published - 1 Jan 2017 |
Externally published | Yes |