Mapping regulatory variants in hiPSC models

Gabriel E. Hoffman; Kristen J. Brennand

doi:10.1038/s41588-017-0017-4

Mapping regulatory variants in hiPSC models

Gabriel E. Hoffman, Kristen J. Brennand

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

A new study illustrates the power of the human induced pluripotent stem cell (hiPSC) platform by studying hiPSC-derived sensory neurons from 107 individuals. In addition to identifying thousands of quantitative trait loci influencing gene expression, chromatin accessibility and RNA splicing, the work highlights several underappreciated challenges in the hiPSC field.

Original language	English
Pages (from-to)	1-2
Number of pages	2
Journal	Nature Genetics
Volume	50
Issue number	1
DOIs	https://doi.org/10.1038/s41588-017-0017-4
State	Published - 1 Jan 2018

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abstract = "A new study illustrates the power of the human induced pluripotent stem cell (hiPSC) platform by studying hiPSC-derived sensory neurons from 107 individuals. In addition to identifying thousands of quantitative trait loci influencing gene expression, chromatin accessibility and RNA splicing, the work highlights several underappreciated challenges in the hiPSC field.",

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Mapping regulatory variants in hiPSC models

Abstract

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