TY - JOUR
T1 - Mapping of the influenza virus genome
T2 - Identification of the hemagglutinin and the neuraminidase genes
AU - Palese, P.
AU - Schulman, J. L.
PY - 1976
Y1 - 1976
N2 - Polyacrylamide gel electrophoresis of the RNA of influenza A/PR/8/34 (H0N1) and A/Hong Kong/8/68 (H3N2) viruses and recombinant viruses derived from them revealed that each contains eight RNA segments, the fourth of which codes for hemagglutinin. (The largest RNA of the segmented genome is counted as band 1.) The neuraminidase gene was identified as the sixth segment in the RNA pattern of influenza A/PR8 virus and as the fifth segment of A/Hong Kong virus. The molecular weights of the RNAs for the hemagglutinin and the neuraminidase genes lie in the range of 600,000-700,000.
AB - Polyacrylamide gel electrophoresis of the RNA of influenza A/PR/8/34 (H0N1) and A/Hong Kong/8/68 (H3N2) viruses and recombinant viruses derived from them revealed that each contains eight RNA segments, the fourth of which codes for hemagglutinin. (The largest RNA of the segmented genome is counted as band 1.) The neuraminidase gene was identified as the sixth segment in the RNA pattern of influenza A/PR8 virus and as the fifth segment of A/Hong Kong virus. The molecular weights of the RNAs for the hemagglutinin and the neuraminidase genes lie in the range of 600,000-700,000.
UR - http://www.scopus.com/inward/record.url?scp=0017064932&partnerID=8YFLogxK
U2 - 10.1073/pnas.73.6.2142
DO - 10.1073/pnas.73.6.2142
M3 - Article
C2 - 1064882
AN - SCOPUS:0017064932
SN - 0027-8424
VL - 73
SP - 2142
EP - 2146
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 6
ER -