Mapping of a major susceptibility locus for graves' disease (GD-1) to chromosome 14q31

Keyphrases

• Susceptibility Loci 100%
• Graves' Disease 100%
• LOD Score 60%
• TSH Receptor 60%
• Hashimoto's Thyroiditis 60%
• Autoimmune Thyroid Disease 60%
• Mode of Inheritance 40%
• Susceptible Individuals 20%
• Receptor Gene 20%
• Dominant Mode 20%
• Susceptibility Genes 20%
• High-score 20%
• Thyroglobulin 20%
• Penetrance 20%
• DNA Markers 20%
• HLA Region 20%
• HLA Genes 20%
• Immunoglobulin Heavy Chain Gene 20%
• Receptor Region 20%
• Thyroid Peroxidase Antibody (TPOAb) 20%
• Cytotoxic T-lymphocyte-associated Protein 4 (CTLA-4) 20%
• Gene Regions 20%
• Disease Susceptibility Genes 20%

Biochemistry, Genetics and Molecular Biology

• Autoimmunity 100%
• Thyrotropin Receptor 100%
• Chromosome 100%
• Candidate Gene 66%
• Inheritance 66%
• Susceptibility Gene 66%
• Gene Linkage 33%
• Receptor Gene 33%
• Penetrance 33%
• Genetic Marker 33%
• CTLA-4 33%
• Thyroid Peroxidase 33%
• Thyroglobulin 33%
• Immunoglobulin Heavy Chain Gene 33%

Immunology and Microbiology

• Graves' Disease 100%
• Chromosome 100%
• Susceptibility 100%
• Hashimoto's Thyroiditis 60%
• Autoimmune Thyroiditis 60%
• Inheritance 40%
• Receptor Gene 20%
• CTLA-4 20%
• Genetic Marker 20%
• Penetrance 20%
• Immunoglobulin Heavy Chain Gene 20%
• Thyroid 20%
• Peroxidase 20%