@article{315409932a7746d493d1b97ec695cede,
title = "MAPK and PI3K signaling: At the crossroads of neural crest development",
abstract = "Receptor tyrosine kinase-mediated growth factor signaling is essential for proper formation and development of the neural crest. The many ligands and receptors implicated in these processes signal through relatively few downstream pathways, frequently converging on the MAPK and PI3K pathways. Despite decades of study, there is still considerable uncertainty about where and when these signaling pathways are required and how they elicit particular responses. This review summarizes our current understanding of growth factor-induced MAPK and PI3K signaling in the neural crest.",
keywords = "AKT, Cell signaling, ERK, Receptor Tyrosine kinases",
author = "Dinsmore, {Colin J.} and Philippe Soriano",
note = "Funding Information: We thank Stuart Aaronson, Katherine Fantauzzo, Robert Krauss, Sergei Sokol, and our laboratory colleagues for discussions and critical comments on the manuscript. We apologize to authors whose work we have not cited due to space limitations. Work from the author's laboratory is supported by NIH/NIDCR Grants R01 DE022363 and R01 DE022778 to P.S. C.J.D. is supported by NIH/NIDCR fellowship F32 DE026678 . Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",
year = "2018",
month = dec,
day = "1",
doi = "10.1016/j.ydbio.2018.02.003",
language = "English",
volume = "444",
pages = "S79--S97",
journal = "Developmental Biology",
issn = "0012-1606",
publisher = "Elsevier Inc.",
}