Mannan-Binding Lectin Promotes Murine Graft-versus-Host Disease by Amplifying Lipopolysaccharide-Initiated Inflammation

Keyphrases

• Inflammation 100%
• Lipopolysaccharide 100%
• Graft-versus-host Disease (GvHD) 100%
• Mannose-binding Lectin 100%
• Antigen-presenting Cells 33%
• Clinical Expression 22%
• T Cells 16%
• Bone Marrow 11%
• Gene-deficient Mice 11%
• T Cell Immunity 11%
• CD4+ 11%
• T Cell Response 11%
• Wild Mice 11%
• Pretransplant 11%
• Interleukin-17 (IL-17) 11%
• Complement Activation 11%
• C1 Esterase Inhibitor 11%
• Weight Loss 5%
• Inflammatory Cytokines 5%
• Gene Expression 5%
• Interleukin-12 (IL-12) 5%
• Overall Survival 5%
• Disease Severity 5%
• CD8+ T Cells 5%
• Interleukin-1β 5%
• Induced Response 5%
• CD11c 5%
• CD11b+ 5%
• In Vitro Study 5%
• Immunization 5%
• T-cell Mediated 5%
• Ovalbumin 5%
• Cell Infiltration 5%
• Oligosaccharides 5%
• Clinical Severity 5%
• Irradiation 5%
• Autoreactive T Cells 5%
• Disease Expression 5%
• Complement Cascade 5%
• Lipopolysaccharide-induced 5%
• Innate Immune Response 5%
• Ligation 5%
• Conditioning Regimen 5%
• Bone Marrow Cells 5%
• Complement Components 5%
• Alternative Pathway 5%
• Complement System 5%
• Allogeneic Cells 5%
• Hematopoietic Stem Cell Transplantation 5%
• Mannose 5%
• CD40 Gene 5%
• Donor Engraftment 5%
• Gastrointestinal Inflammation 5%
• Lipoteichoic Acid 5%
• Gastrointestinal Integrity 5%

Immunology and Microbiology

• Graft-Versus-Host Disease 100%
• Mannan-Binding Lectin 100%
• Antigen-Presenting Cell 33%
• Wild Type 27%
• T Cell 27%
• Adoptive Immunity 11%
• CD4 11%
• Wild Type Mouse 11%
• Complement Activation 11%
• C1-Inhibitor 11%
• T Cell Receptor 5%
• Proinflammatory Cytokine 5%
• Cytotoxic T-Cell 5%
• Cell Activation 5%
• CD11c 5%
• Gene Expression 5%
• Overall Survival 5%
• Engraftment 5%
• Cell Infiltration 5%
• Conditioning 5%
• Complement System 5%
• Hematopoietic Stem Cell Transplantation 5%
• Alloreactive T Cell 5%
• Bone Marrow Cell 5%
• Lipoteichoic Acid 5%
• Innate Immune Cell 5%
• In Vitro 5%