Management of Isoimmunized Pregnancy

Rosemary Reiss; Jay D. Iams; Richard O'shaughnessy; Leandro Cordero; Melanie Kennedy; Patricia Strohm; J. M. Bowman; F. A. Manning; C. Harman; Fredric D. Frigoletto; Michael F. Greene; Beryl R. Benacerraf; Vanessa Barss; Daniel H. Saltzman

doi:10.1056/NEJM198701153160312

Management of Isoimmunized Pregnancy

Rosemary Reiss, Jay D. Iams, Richard O'shaughnessy, Leandro Cordero, Melanie Kennedy, Patricia Strohm, J. M. Bowman, F. A. Manning, C. Harman, Fredric D. Frigoletto, Michael F. Greene, Beryl R. Benacerraf, Vanessa Barss, Daniel H. Saltzman

Research output: Contribution to journal › Letter › peer-review

1 Scopus citations

Abstract

To the Editor: We are not surprised that Frigoletto et al. report good outcomes without intrauterine transfusion in pregnancies with rhesus sensitization, described in their recent article (Aug. 14 issue).¹ Except for one value of 0.395, the amniotic-fluid optical-density difference at 450 nm (ΔOD 450) in all cases was between 0.162 and 0.26. Few would advocate routine intrauterine transfusions for fetuses without hydrops whose amniotic fluid had optical densities in this range. Even an Rh-negative infant can occasionally have values of 0.2 to 0.25 at 22 to 24 weeks.² Serial amniocenteses, ultrasound examinations, and nonstress tests are needed to guide…

Original language	English
Pages (from-to)	165-166
Number of pages	2
Journal	New England Journal of Medicine
Volume	316
Issue number	3
DOIs	https://doi.org/10.1056/NEJM198701153160312
State	Published - 15 Jan 1987
Externally published	Yes

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@article{119ab50210c840b99e317de8b1d16e68,

title = "Management of Isoimmunized Pregnancy",

abstract = "To the Editor: We are not surprised that Frigoletto et al. report good outcomes without intrauterine transfusion in pregnancies with rhesus sensitization, described in their recent article (Aug. 14 issue).1 Except for one value of 0.395, the amniotic-fluid optical-density difference at 450 nm (ΔOD 450) in all cases was between 0.162 and 0.26. Few would advocate routine intrauterine transfusions for fetuses without hydrops whose amniotic fluid had optical densities in this range. Even an Rh-negative infant can occasionally have values of 0.2 to 0.25 at 22 to 24 weeks.2 Serial amniocenteses, ultrasound examinations, and nonstress tests are needed to guide…",

author = "Rosemary Reiss and Iams, {Jay D.} and Richard O'shaughnessy and Leandro Cordero and Melanie Kennedy and Patricia Strohm and Bowman, {J. M.} and Manning, {F. A.} and C. Harman and Frigoletto, {Fredric D.} and Greene, {Michael F.} and Benacerraf, {Beryl R.} and Vanessa Barss and Saltzman, {Daniel H.}",

year = "1987",

month = jan,

day = "15",

doi = "10.1056/NEJM198701153160312",

language = "English",

volume = "316",

pages = "165--166",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachussetts Medical Society",

number = "3",

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TY - JOUR

T1 - Management of Isoimmunized Pregnancy

AU - Reiss, Rosemary

AU - Iams, Jay D.

AU - O'shaughnessy, Richard

AU - Cordero, Leandro

AU - Kennedy, Melanie

AU - Strohm, Patricia

AU - Bowman, J. M.

AU - Manning, F. A.

AU - Harman, C.

AU - Frigoletto, Fredric D.

AU - Greene, Michael F.

AU - Benacerraf, Beryl R.

AU - Barss, Vanessa

AU - Saltzman, Daniel H.

PY - 1987/1/15

Y1 - 1987/1/15

N2 - To the Editor: We are not surprised that Frigoletto et al. report good outcomes without intrauterine transfusion in pregnancies with rhesus sensitization, described in their recent article (Aug. 14 issue).1 Except for one value of 0.395, the amniotic-fluid optical-density difference at 450 nm (ΔOD 450) in all cases was between 0.162 and 0.26. Few would advocate routine intrauterine transfusions for fetuses without hydrops whose amniotic fluid had optical densities in this range. Even an Rh-negative infant can occasionally have values of 0.2 to 0.25 at 22 to 24 weeks.2 Serial amniocenteses, ultrasound examinations, and nonstress tests are needed to guide…

AB - To the Editor: We are not surprised that Frigoletto et al. report good outcomes without intrauterine transfusion in pregnancies with rhesus sensitization, described in their recent article (Aug. 14 issue).1 Except for one value of 0.395, the amniotic-fluid optical-density difference at 450 nm (ΔOD 450) in all cases was between 0.162 and 0.26. Few would advocate routine intrauterine transfusions for fetuses without hydrops whose amniotic fluid had optical densities in this range. Even an Rh-negative infant can occasionally have values of 0.2 to 0.25 at 22 to 24 weeks.2 Serial amniocenteses, ultrasound examinations, and nonstress tests are needed to guide…

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VL - 316

SP - 165

EP - 166

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 3

ER -

Management of Isoimmunized Pregnancy

Abstract

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