TY - JOUR
T1 - Management of Hepatitis B in Pregnancy
AU - Rios, Jeanette
AU - Aliasi-Sinai, Lital
AU - Schmidt, Natalia
AU - Kushner, Tatyana
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
PY - 2024/6
Y1 - 2024/6
N2 - Purpose of Review: In 2016, WHO sets a target to eliminate viral hepatitis as a public health threat by 2030, with significant emphasis placed on reducing MTCT of HBV, which is the leading cause of CHB worldwide. In this review, we discuss the most recent recommendations in the literature on the management of HBV in pregnancy, including treatment considerations during pregnancy and recommendations for infant management, to reduce the MTCT of HBV. Recent Findings: Recent research advancements have focused on further unraveling the safety and efficacy of treatment options during pregnancy, developing more accessible postnatal immunoprophylaxis regimens, and exploring theoretical models for HBV treatment during pregnancy aimed at preventing MTCT. Summary: Despite considerable public health efforts, HBV remains a significant global health concern. Effective collaboration among clinicians is essential for appropriate screening, assessment, treatment during and after pregnancy, and proper follow-up, in order to reduce the MTCT of HBV and optimize maternal health outcomes.
AB - Purpose of Review: In 2016, WHO sets a target to eliminate viral hepatitis as a public health threat by 2030, with significant emphasis placed on reducing MTCT of HBV, which is the leading cause of CHB worldwide. In this review, we discuss the most recent recommendations in the literature on the management of HBV in pregnancy, including treatment considerations during pregnancy and recommendations for infant management, to reduce the MTCT of HBV. Recent Findings: Recent research advancements have focused on further unraveling the safety and efficacy of treatment options during pregnancy, developing more accessible postnatal immunoprophylaxis regimens, and exploring theoretical models for HBV treatment during pregnancy aimed at preventing MTCT. Summary: Despite considerable public health efforts, HBV remains a significant global health concern. Effective collaboration among clinicians is essential for appropriate screening, assessment, treatment during and after pregnancy, and proper follow-up, in order to reduce the MTCT of HBV and optimize maternal health outcomes.
KW - Antiviral therapy
KW - Hepatitis B virus
KW - Mother to child transmission
KW - Pregnancy
KW - Vertical transmission
UR - http://www.scopus.com/inward/record.url?scp=85195607319&partnerID=8YFLogxK
U2 - 10.1007/s11901-024-00659-2
DO - 10.1007/s11901-024-00659-2
M3 - Review article
AN - SCOPUS:85195607319
SN - 1540-3416
VL - 23
SP - 278
EP - 286
JO - Current Hepatitis Reports
JF - Current Hepatitis Reports
IS - 2
ER -