Management of drug-eluting stent restenosis

Kiyotake Ishikawa, Yutaka Aoyama, Haruo Hirayama

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


In-stent restenosis has been a longstanding problem after percutaneous coronary intervention. The introduction of the drug-eluting stent (DES) successfully reduced the rate of restenosis; however, it is not completely diminished. Although restenosis occurs less frequently compared to the bare-metal stent (BMS), DES restenosis remains a familiar problem due to the increasing total number of implanted DESs as well as the targeting of more complex lesions. In addition, worse outcomes after repeat revascularization compared to BMS restenosis are reported in DES restenosis. Management of DES restenosis is an emerging issue, which requires careful evaluation of the restenosed lesion, together with cautious determination of therapeutic strategy. In this review, available repeat revascularization procedures for DES restenosis as well as possible impacting factors on the outcomes are discussed.

Original languageEnglish
Pages (from-to)178-182
Number of pages5
JournalJournal of Invasive Cardiology
Issue number4
StatePublished - Apr 2012


  • CABG versus PCI
  • coronary interventions
  • in-stent restenosis
  • stenting


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