Mallory‐weiss syndrome secondary to cis‐platinum chemotherapy: An unusual complication

Stephane Lubicz, Michail Shafir, Sharon Diamond, Robert Monosan, Carmel Cohen

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The Mallory‐Weiss syndrome is a relatively infrequent cause of digestive tract bleeding and most cases have been described in alcoholics. Nonoperative management is frequently successful. We present here a case of sudden onset of wretching and vomiting after IV infusion of cis‐platinum for recurrent carcinoma of the uterine cervix in which the patient had profuse hematemesis secondary to three posterior gastroesophageal tears requiring operative intervention after failure of nonsurgical management. This is an unusual complication of antineoplastic chemotherapy and its prevention is emphasized in this paper.

Original languageEnglish
Pages (from-to)247-249
Number of pages3
JournalJournal of Surgical Oncology
Volume20
Issue number4
DOIs
StatePublished - Aug 1982

Keywords

  • Mallory‐Weiss syndrome
  • cis‐platinum

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