Malignant degeneration of pilonidal disease in an immunosuppressed patient: Report of a case and review of the literature

Marcus M. Malek; Patrick O. Emanuel; Celia M. Divino

doi:10.1007/s10350-007-0267-9

Malignant degeneration of pilonidal disease in an immunosuppressed patient: Report of a case and review of the literature

Marcus M. Malek, Patrick O. Emanuel, Celia M. Divino

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

PURPOSE: This report was designed to discuss the case of a patient taking immunosuppression after transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst and to examine the reported literature on malignant degeneration of pilonidal disease. METHODS: We performed a comprehensive literature review and examined the medical record of a patient taking immunosuppressive medications after renal transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst located at the superior gluteal cleft. CONCLUSIONS: Pilonidal disease is a common condition, and it is important to know that malignancy can arise when the disease is chronic. Immunosuppression and human papillomavirus infection may be predisposing factors to malignant degeneration of pilonidal cysts and may accelerate the transformation.

Original language	English
Pages (from-to)	1475-1477
Number of pages	3
Journal	Diseases of the Colon and Rectum
Volume	50
Issue number	9
DOIs	https://doi.org/10.1007/s10350-007-0267-9
State	Published - Sep 2007

Keywords

Carcinoma
Immunosuppression
Malignant
Pilonidal
Transplant

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title = "Malignant degeneration of pilonidal disease in an immunosuppressed patient: Report of a case and review of the literature",

abstract = "PURPOSE: This report was designed to discuss the case of a patient taking immunosuppression after transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst and to examine the reported literature on malignant degeneration of pilonidal disease. METHODS: We performed a comprehensive literature review and examined the medical record of a patient taking immunosuppressive medications after renal transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst located at the superior gluteal cleft. CONCLUSIONS: Pilonidal disease is a common condition, and it is important to know that malignancy can arise when the disease is chronic. Immunosuppression and human papillomavirus infection may be predisposing factors to malignant degeneration of pilonidal cysts and may accelerate the transformation.",

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AU - Malek, Marcus M.

AU - Emanuel, Patrick O.

AU - Divino, Celia M.

PY - 2007/9

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N2 - PURPOSE: This report was designed to discuss the case of a patient taking immunosuppression after transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst and to examine the reported literature on malignant degeneration of pilonidal disease. METHODS: We performed a comprehensive literature review and examined the medical record of a patient taking immunosuppressive medications after renal transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst located at the superior gluteal cleft. CONCLUSIONS: Pilonidal disease is a common condition, and it is important to know that malignancy can arise when the disease is chronic. Immunosuppression and human papillomavirus infection may be predisposing factors to malignant degeneration of pilonidal cysts and may accelerate the transformation.

AB - PURPOSE: This report was designed to discuss the case of a patient taking immunosuppression after transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst and to examine the reported literature on malignant degeneration of pilonidal disease. METHODS: We performed a comprehensive literature review and examined the medical record of a patient taking immunosuppressive medications after renal transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst located at the superior gluteal cleft. CONCLUSIONS: Pilonidal disease is a common condition, and it is important to know that malignancy can arise when the disease is chronic. Immunosuppression and human papillomavirus infection may be predisposing factors to malignant degeneration of pilonidal cysts and may accelerate the transformation.

KW - Carcinoma

KW - Immunosuppression

KW - Malignant

KW - Pilonidal

KW - Transplant

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Malignant degeneration of pilonidal disease in an immunosuppressed patient: Report of a case and review of the literature

Abstract

Keywords

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