The records of 228 patients with acute leukemia admitted to Roswell Park Memorial Institute from 1967 through 1971 were reviewed. One hundred twenty patients with acute lymphocytic leukemia (ALL) and 108 with acute myelocytic leukemia (AML) were studied. Ten major abdominal or thoracic procedures were performed in 9 patients with AML. Five patients were markedly thrombocytopenic. One had severe bleeding at the time of surgery and died within 12 hours. Another patient developed an undiagnosed hemothorax after a thoracotomy and died in 1 week. A third patient succumbed with severe bronchopneumonia 6 days following an operation for an abdominal infection. Six of the 9 patients survived longer than 1 month postoperatively. Proper operative procedures and supportive care should facilitate major surgery, when indicated in patients with acute myelocytic leukemia.
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|Published - Oct 1974