Maintenance of parathyroid hormone response in clonal rat osteosarcoma lines

Robert J. Majeska; Sevgi B. Rodan; Gideon A. Rodan

doi:10.1016/0014-4827(78)90193-3

Maintenance of parathyroid hormone response in clonal rat osteosarcoma lines

Robert J. Majeska, Sevgi B. Rodan, Gideon A. Rodan

Research output: Contribution to journal › Article › peer-review

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Abstract

Clonal cell lines possessing parathyroid hormone-stimulated adenylate cyclase were established from a rat osteosarcoma. These lines have retained undiminished hormone responsiveness through more than 5 months in continuous culture. Both the extent stimulation and hormone sensitivity were similar to those found in freshly excised tumor and embryonic bone.

Original language	English
Pages (from-to)	465-468
Number of pages	4
Journal	Experimental Cell Research
Volume	111
Issue number	2
DOIs	https://doi.org/10.1016/0014-4827(78)90193-3
State	Published - Feb 1978
Externally published	Yes

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title = "Maintenance of parathyroid hormone response in clonal rat osteosarcoma lines",

abstract = "Clonal cell lines possessing parathyroid hormone-stimulated adenylate cyclase were established from a rat osteosarcoma. These lines have retained undiminished hormone responsiveness through more than 5 months in continuous culture. Both the extent stimulation and hormone sensitivity were similar to those found in freshly excised tumor and embryonic bone.",

author = "Majeska, {Robert J.} and Rodan, {Sevgi B.} and Rodan, {Gideon A.}",

year = "1978",

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AU - Rodan, Sevgi B.

AU - Rodan, Gideon A.

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AB - Clonal cell lines possessing parathyroid hormone-stimulated adenylate cyclase were established from a rat osteosarcoma. These lines have retained undiminished hormone responsiveness through more than 5 months in continuous culture. Both the extent stimulation and hormone sensitivity were similar to those found in freshly excised tumor and embryonic bone.

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DO - 10.1016/0014-4827(78)90193-3

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JO - Experimental Cell Research

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Maintenance of parathyroid hormone response in clonal rat osteosarcoma lines

Abstract

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