Magnetic resonance evaluation of the associations of thoracic and abdominal aortic plaques with the presence and extent of coronary artery stenosis

Kazuhiro Ashida, Yukihiko Momiyama, Zahi A. Fayad, Nobukiyo Tanaka, Ryuichi Kato, Hiroaki Taniguchi, Reiko Ohmori, Teruyoshi Kihara, Akira Kameyama, Masayoshi Nagata, Haruo Nakamura, Fumitaka Ohsuzu

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The association between coronary artery disease (CAD) and thoracic aortic plaques has often been reported using transesophageal echocardiography. However, studies showing the association between CAD and abdominal aortic plaques are scarce. CMR can visualize plaques in both the thoracic and abdominal aortas. Using CMR, we investigated the associations of thoracic and abdominal aortic plaques with the presence and extent of coronary artery stenosis in 146 patients undergoing coronary angiography, of whom 108 had CAD. The prevalence of thoracic and abdominal aortic plaques was higher in patients with CAD than in those without CAD (73% and 94% vs. 32% and 79%, p < 0.025). Stepwise increases in the prevalence and extents of both thoracic and abdominal plaques were found depending on the number of stenotic coronary vessels. Plaque extent in the thoracic aorta correlated with the numbers of > 50% and > 25% stenotic coronary segments (rs = 0.30 and 0.41). Plaque extent in the abdominal aorta also correlated with the numbers of > 50% and > 25% stenotic segments (rs = 0.40 and 0.44). Notably, the total plaque extent in the aortas correlated best with the numbers of > 50% and > 25% stenotic coronary segments (rs = 0.41 and 0.49, p < 0.001), and this factor was found to be the best predictor for the presence of CAD by the receiver-operating- characteristics curve analysis. Thus, the total plaque extent in the aortas was found to be more closely associated with the presence and extent of coronary stenosis than the thoracic or abdominal aortic plaque extent.

Original languageEnglish
Pages (from-to)855-861
Number of pages7
JournalJournal of Cardiovascular Magnetic Resonance
Volume9
Issue number6
DOIs
StatePublished - Nov 2007

Keywords

  • Aorta
  • Coronary Artery Disease
  • Plaque

Fingerprint

Dive into the research topics of 'Magnetic resonance evaluation of the associations of thoracic and abdominal aortic plaques with the presence and extent of coronary artery stenosis'. Together they form a unique fingerprint.

Cite this