Original language | English |
---|---|
Article number | e027736 |
Journal | Journal of the American Heart Association |
Volume | 12 |
Issue number | 8 |
DOIs | |
State | Published - 18 Apr 2023 |
Keywords
- hereditary cardiac amyloidosis
- metabolomics
- prealbumin
- random forest classification
- restrictive cardiomyopathy
- transthyretin
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In: Journal of the American Heart Association, Vol. 12, No. 8, e027736, 18.04.2023.
Research output: Contribution to journal › Letter › peer-review
TY - JOUR
T1 - Machine Learning Identifies Plasma Metabolites Associated With Heart Failure in Underrepresented Populations With the TTR V122I Variant
AU - Park, Joshua K.
AU - Petrazzini, Ben O.
AU - Saha, Aparna
AU - Vaid, Akhil
AU - Vy, Ha My T.
AU - Márquez-Luna, Carla
AU - Chan, Lili
AU - Nadkarni, Girish N.
AU - Do, Ron
N1 - Funding Information: RD reported receiving grants from AstraZeneca; grants and nonfinancial support from Goldfinch Bio; being a scientific co-founder and equity holder for Pensieve Health; and being a consultant for Variant Bio, all unrelated to this work. GNN reported being a scientific co-founder, consultant, advisory board member, and equity owner of Renalytix AI; being a scientific co-founder and equity holder for Pensieve Health; being a consultant for Variant Bio; receiving grants from Goldfinch Bio; and receiving personal fees from Renalytix, BioVie, Reata, AstraZeneca, Menarini Health, Daiichi Sankyo, Cambridge Consulting, Qiming Capital and GLG Consulting, all unrelated to this work. Funding Information: RD is supported by National Institutes of Health grants R35-GM124836, R01-HL139865, and R01-HL155915. GNN is supported by National Institutes of Health grants R01-DK108803 and R01-HL155915. JKP is supported by National Institutes of Health grant 5T32GM007280-44. CML is supported by National Institutes of Health grant 5T32HL00782424.
PY - 2023/4/18
Y1 - 2023/4/18
KW - hereditary cardiac amyloidosis
KW - metabolomics
KW - prealbumin
KW - random forest classification
KW - restrictive cardiomyopathy
KW - transthyretin
UR - http://www.scopus.com/inward/record.url?scp=85152625440&partnerID=8YFLogxK
U2 - 10.1161/JAHA.122.027736
DO - 10.1161/JAHA.122.027736
M3 - Letter
C2 - 37042260
AN - SCOPUS:85152625440
SN - 2047-9980
VL - 12
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 8
M1 - e027736
ER -