Lymphocyte Function in Major Depressive Disorder

Steven J. Schleifer; Steven E. Keller; Arthur T. Meyerson; Marjorie J. Raskin; Kenneth L. Davis; Marvin Stein

doi:10.1001/archpsyc.1984.01790160070008

Lymphocyte Function in Major Depressive Disorder

Steven J. Schleifer
, Steven E. Keller
, Arthur T. Meyerson
, Marjorie J. Raskin
, Kenneth L. Davis
, Marvin Stein

Research output: Contribution to journal › Article › peer-review

309 Scopus citations

Abstract

Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.

Original language	English
Pages (from-to)	484-486
Number of pages	3
Journal	Archives of General Psychiatry
Volume	41
Issue number	5
DOIs	https://doi.org/10.1001/archpsyc.1984.01790160070008
State	Published - May 1984
Externally published	Yes

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title = "Lymphocyte Function in Major Depressive Disorder",

abstract = "Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.",

author = "Schleifer, \{Steven J.\} and Keller, \{Steven E.\} and Meyerson, \{Arthur T.\} and Raskin, \{Marjorie J.\} and Davis, \{Kenneth L.\} and Marvin Stein",

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AU - Schleifer, Steven J.

AU - Keller, Steven E.

AU - Meyerson, Arthur T.

AU - Raskin, Marjorie J.

AU - Davis, Kenneth L.

AU - Stein, Marvin

PY - 1984/5

Y1 - 1984/5

N2 - Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.

AB - Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.

UR - https://www.scopus.com/pages/publications/0021365270

U2 - 10.1001/archpsyc.1984.01790160070008

DO - 10.1001/archpsyc.1984.01790160070008

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AN - SCOPUS:0021365270

SN - 0003-990X

VL - 41

SP - 484

EP - 486

JO - Archives of General Psychiatry

JF - Archives of General Psychiatry

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ER -

Lymphocyte Function in Major Depressive Disorder

Abstract

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